莫西沙星与左氧氟沙星在临床应用中的成本-效果分析

目的 探讨莫西沙星和左氧氟沙星在下呼吸道感染治疗中所产生的经济效果。方法根据文献选择下呼吸道感染患者98例，随机分成莫西沙星组（A组）和左氧氟沙星组（B组），分别给予治疗。运用药物经济学的成本．效果分析方法进行分析评价。结果 A组、B组治疗有效率分别为93．88％和89．80％，不良反应发生率分别为10．20％和8．16％，细菌清除率分别为97．37％和91．18％。结论 两组方案治疗下呼吸道感染的临床有效率、治愈率无显著差异，但A组的细菌清除率优于B组，B组的经济学成本优于A组。

Application of costeffectiveness analysis in moxifloxacin and levofloxacin for the treatment lower respiratory tract infection

Objective To evaluate the eeonomic effect of moxifloxaein injection and levofloxacin injection in treating lower respiratory tract infection. Methods According to literature, 98 patients were chosen and divided randomly into team A （moxifloxacin） and team B （levofloxaein）. These two categories of patients were given separate treatments which were analyzed and appraised by the cost-effect method in pharmacoeconomic research. Results the overall clinical effective rate for team A was 93.88% and for team B was 89. 80%. Occurrenee of the adverse reaction for team A was 10. 20% and for B was 8.16% , the bacterial clearance rate for team A was97.37% and for team B was 91.18%. Conclusion with these two kinds of treatment,there is no significant difference in clinical effective rate and cure rate for lower respiratory tract infection. But the bacterial clearance rate of team A was better than that of team B, and economic cost of team B was better than that of team A