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Daily Short Message Service Surveys to Measure Sexual Behavior and Pre-exposure Prophylaxis Use Among Kenyan Men and Women |
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| Authors: | Kathryn Curran Nelly R Mugo Ann Kurth Kenneth Ngure Renee Heffron Deborah Donnell Connie Celum Jared M Baeten |
| Institution: | 1. Department of Epidemiology, University of Washington, Seattle, WA, USA 2. Department of Global Health, University of Washington, 325 Ninth Avenue, Box 359927, Seattle, WA, 98104, USA 5. Department of Obstetrics and Gynaecology, Kenyatta National Hospital, Nairobi, Kenya 4. School of Nursing, University of Washington, Seattle, WA, USA 6. College of Nursing, New York University, New York, NY, USA 7. Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya 8. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA 3. Department of Medicine, University of Washington, Seattle, WA, USA |
| Abstract: | Pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy which requires high adherence. We tested the use of daily short message service (i.e., SMS/text message) surveys to measure sexual behavior and PrEP adherence in Kenya. Ninety-six HIV-uninfected adult individuals, taking daily oral PrEP in a clinical trial, received daily SMS surveys for 60 days. Most participants (96.9 %) reported taking PrEP on ≥80 % days, but 69.8 % missed at least one dose. Unprotected sex was reported on 4.9 % of days; however, 47.9 % of participants reported unprotected sex at least once. Unprotected sex was not correlated with PrEP use (OR = 0.95). Participants reporting more sex were less likely to report PrEP non-adherence and those reporting no sex were most likely to report missing a PrEP dose (adjusted OR = 1.87). PrEP adherence was high, missed doses were correlated with sexual abstinence, and unprotected sex was not associated with decreased PrEP adherence. |
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