| Correlation of the amount of AgNORs with the grading and prognosis of bladder tumour |
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| 引用本文： | 叶定伟,郑家富,钱松溪,马永江,龚志锦. Correlation of the amount of AgNORs with the grading and prognosis of bladder tumour[J]. 中国人民解放军军医大学学报, 1992, 0(3) |
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| 作者姓名： | 叶定伟 郑家富 钱松溪 马永江 龚志锦 |
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| 作者单位： | Department of Urology Changhai Hospital，Second Military Medical University，Shanghai 200433，Department of Urology，Changhai Hospital，Second Military Medical University，Shanghai 200433，Department of Urology，Changhai Hospital，Second Military Medical University，Shanghai 200433，Department of Urology，Changhai Hospital，Second Military Medical University，Shanghai 200433，Department of Pathoanatomy，Second Military Medical University，Shanghai 200433 |
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| 摘 要： | The number of AgNORs in the nucleolar organizer region was studied quantitativelyby one-step silver colloid technique in 6 samples obtained from normal bladder tissue,9 ofchronic cystitis and 56 of transitional cell carcinoma of bladder.The results revealed that meannumber of AgNORs per nucleus was not statistically different between normal bladder tissueand tissue from chronic cystitis,while there was a significant difference between normal or in-flammatory tissue and malignant tisssue on the one hand and between various grades of bladdertumor on the other.The results also indicated that mean number of AgNORs per nucleus wasclosely related to the prognosis of bladder tumor.So it is suggested that AgNOR counting bythe silver stain technique might play a role in the differenciation of benign and malignant lesionsand in grading and prognosis in bladder tumors.
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Correlation of the amount of AgNORs with the grading and prognosis of bladder tumour |
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| Ye Dingwei,Zheng Jiafu,Qian Songxi,Ma Yongjiang,Gong Zhijin. Correlation of the amount of AgNORs with the grading and prognosis of bladder tumour[J]. Journal of Medical Colleges of PLA(China), 1992, 0(3) |
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| Authors: | Ye Dingwei Zheng Jiafu Qian Songxi Ma Yongjiang Gong Zhijin |
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| Affiliation: | Ye Dingwei,Zheng Jiafu,Qian Songxi,Ma Yongjiang,Gong Zhijin Department of Urology,Changhai Hospital,Second Military Medical University,Shanghai 200433 Department of Pathoanatomy,Second Military Medical University,Shanghai 200433 |
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| Abstract: | The number of AgNORs in the nucleolar organizer region was studied quantitatively by one-step silver colloid technique in 6 samples obtained from normal bladder tissue,9 of chronic cystitis and 56 of transitional cell carcinoma of bladder.The results revealed that mean number of AgNORs per nucleus was not statistically different between normal bladder tissue and tissue from chronic cystitis,while there was a significant difference between normal or in- flammatory tissue and malignant tisssue on the one hand and between various grades of bladder tumor on the other.The results also indicated that mean number of AgNORs per nucleus was closely related to the prognosis of bladder tumor.So it is suggested that AgNOR counting by the silver stain technique might play a role in the differenciation of benign and malignant lesions and in grading and prognosis in bladder tumors. |
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| Keywords: | bladder neoplasms nucleolus organizer region silver proteins pathology surgery human |
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