| 血浆醛固酮与肾素活性比值在原发性醛固酮增多症筛查中的应用现状及影响因素 |
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| 引用本文： | 鄞国书,严励. 血浆醛固酮与肾素活性比值在原发性醛固酮增多症筛查中的应用现状及影响因素[J]. 中国实用内科杂志, 2010, 30(1): 19 |
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| 作者姓名： | 鄞国书 严励 |
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| 作者单位： | 中山大学附属第二附属医院内分泌科; |
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| 摘 要： | 血浆醛固酮与肾素活性比值(ARR)是原发性醛固酮增多症(PA)的一个敏感筛查指标,也是评价PA手术预后的指标之一。探讨血浆醛固酮与肾素活性比值测定的影响因素特别是药物、盐负荷和体位的影响对提高ARR的筛查效率具有重要意义。本文就ARR目前的应用情况,测定条件的优化做一介绍。
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| 关 键 词： | 血浆醛固酮 血浆肾素活性 血浆醛固酮/肾素活性比值 原发性醛固酮增多症 |
Ratio of plasma aldosterone concentration to renin activity in screening for primary aldosteronism:the current situation and influencing factors |
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| YIN Guo-shu,YAN Li. Ratio of plasma aldosterone concentration to renin activity in screening for primary aldosteronism:the current situation and influencing factors[J]. Chinese Journal of Practical Internal Medicine, 2010, 30(1): 19 |
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| Authors: | YIN Guo-shu YAN Li |
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| Affiliation: | YIN Guo-shu,YAN Li.Department of Endocrinology,the Second Affiliated Hospital,Sun Yat-sen University,Guangzhou 510120,China |
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| Abstract: | The ratio of plasma aldosterone concentration to renin activity (ARR) is a sensitive parameter for screening of primary aldosteronism (PA) and for predicting prognosis after adrenalectomy in patients with PA.Study of the influencing factors for ARR,especially medications,sodium intake and posture,is of great significance for improving the screen efficacy of ARR.This paper introduces the current application of ARR in screening for PA and optimization of its determining conditions. |
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| Keywords: | aldosterone plasma rennin activity aldosterone/renin ratio primary aldosteronism |
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