| ABO血型不合对HLA相合异基因外周血干细胞移植的影响 |
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| 引用本文： | 宋晓玲,孙竞,范志平,刘启发,江千里,李敏.ABO血型不合对HLA相合异基因外周血干细胞移植的影响[J].热带医学杂志,2011,11(9):1007-1010. |
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| 作者姓名： | 宋晓玲 孙竞 范志平 刘启发 江千里 李敏 |
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| 作者单位： | 南方医科大学南方医院血液科,广东广州,510515 |
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| 摘 要： | 目的在非血缘移植比例增加、移植物抗宿主病(GVHD)发生率增加、免疫抑制剂用量加大的情况下,分析ABO血型不合对HLA相合异基因外周血干细胞移植(allo-BPSCT)的影响。方法将43例ABO血型不合的allo-PBSCT患者与同期49例ABO血型相合的受者进行比较。结果 ABO血型不合组与相合组输注红细胞量分别为(7.73±7.61)u和(4.33±3.24)u(P=0.040),ABO血型不合组与相合组血红蛋白恢复到100g/L的时间分别为(54.08±45.24)d和(32.46±16.95)d(P=0.009)。ABO血型不合组较相合组红细胞输注量多,红系恢复时间长。两组间移植相关并发症差异无统计学意义。结论 ABO血型不合不影响造血干细胞移植的植活、主要合并症及预后。ABO血型不合组较相合组红细胞输注量多,红系恢复较慢。
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| 关 键 词： | 造血干细胞移植 血型不合 ABO血型系统 |
The effects of ABO incompatible on HLA matched allogeneic peripheral blood stem cell transplantation |
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| SONG Xiao-ling,SUN Jing,FAN Zhi-ping,LIU Qi-fa,JIANG Qian-li,LI Min.The effects of ABO incompatible on HLA matched allogeneic peripheral blood stem cell transplantation[J].Journal Of Tropical Medicine,2011,11(9):1007-1010. |
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| Authors: | SONG Xiao-ling SUN Jing FAN Zhi-ping LIU Qi-fa JIANG Qian-li LI Min |
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| Institution: | SONG Xiao-ling,SUN Jing,FAN Zhi-ping,LIU Qi-fa,JIANG Qian-li,LI Min(Department of Hematology,Nanfang Hospital,Southern Medical University,Guangdong,Guangzhou 510515,China) |
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| Abstract: | Objective In the case of un-related transplant proportion,GVHD incidence and the amount of immunosuppressive drugs increased,We analyze the effects of ABO incompatibility on HLA matched allogeneic peripheral blood stem cell transplantation(allo-BPSCT).Methods We compared 43 cases of ABO incompatibility patients with the same period 49 cases of ABO-matched patients who have been carried out allo-PBSCT in our hospital.Results ABO incompatibility group patients need more red blood cell transfusions,and red blo... |
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| Keywords: | hematopoietic stem cell transplantation blood group incompatibility ABO blood group system |
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