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2010年云浮市手足口病病原学监测结果分析
引用本文:欧庆华,崔楚平,张华,彭力荇.2010年云浮市手足口病病原学监测结果分析[J].中国热带医学,2011,11(10):1241-1242.
作者姓名:欧庆华  崔楚平  张华  彭力荇
作者单位:云浮市疾病预防控制中心,广东云浮,527300
摘    要:目的对2010年云浮市哨点医院手足口病(HFMD)监测结果进行分析,了解云浮市手足口病的病原学特征,为云浮市手足口病的防治提供科学的依据。方法收集73例监测哨点医院手足口病病例送检的粪便标本,应用Real time—PCR技术检测肠道病毒7l型(EV71)、柯萨奇病毒A组16型(CAl6)、非EV7l和CAl6的其它肠道病毒核酸。结果 73例手足口病患者中42例为肠道病毒核酸阳性,阳性率为57.5%,其中EV71病毒、CAl6病毒以及非EV7l和CAl6的其它肠道病毒分别占总阳性数的71.4%、7.1%、21.4%。三种不同型别肠道病毒在全年中交替变更;病毒检出高峰出现在5~6月,病例人群男性高于女性(1.92:1),4岁以下儿童病例阳性率最高。结论云浮市2010年手足口病疫情发病高峰为5-6月,4岁以下儿童病例发病数最多,肠道病毒EV71型是2010年云浮市手足口病流行的主要毒株类型。开展手足口病流行病学和病原学研究,将有助于提出更好的预防和控制措施。

关 键 词:手足口病  流行特征  Realtime-PCR  肠道病毒EV71型

Results of panthogenic sentinel monitoring of HFMD in Yunfu City in 2010
OU Qing-hua,CUI Chu-ping,ZHANG Hua,et al..Results of panthogenic sentinel monitoring of HFMD in Yunfu City in 2010[J].China Tropical Medicine,2011,11(10):1241-1242.
Authors:OU Qing-hua  CUI Chu-ping  ZHANG Hua  
Institution:OU Qing-hua,CUI Chu-ping,ZHANG Hua,et al.(Yunfu Municipal Center for Disease Control and Prevention,Yunfu 527300,Guangdong,P.R.China)
Abstract:Objective To analyze the pathogenic sentinel moitoring of hand-foot-mouth disease(HFMD) from in Yunfu city in 2010.Method Totally 73 sample of clinical HFMD feces samples were collected from monitor hospital.Nucleic acids of three type of viruses of enterovirus 71(EV71),Coxsackie virus A16(CA16) and other enterovirus were detected by Real-time PCR method.Results There 42 HFMD samples were tested positive for enterovirus with a positive rate of 57.5%.The positive detectable rate of EV71,CA16,Not EV71 or CA16...
Keywords:HFMD  Epidemic characteristic  Real-time PCR  EV71  
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