| 诺丽果粉食用安全性研究 |
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| 引用本文： | 林卫华,郑定仙,冯丁山,王湛,黄业宇,吴爱琴. 诺丽果粉食用安全性研究[J]. 中国热带医学, 2011, 11(12): 1509-1511 |
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| 作者姓名： | 林卫华 郑定仙 冯丁山 王湛 黄业宇 吴爱琴 |
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| 作者单位： | 海南省疾病预防控制中心,海南海口,570203 |
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| 基金项目： | 海南省卫生厅科研立项课题(No.琼卫2009-3) |
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| 摘 要： | 目的对诺丽果粉的毒性和致突变性进行探讨,了解其食用安全性。方法采用急性毒性试验、骨髓细胞微核试验、小鼠精子畸形试验、Ames试验、30d喂养试验进行检测。结果诺丽果粉雌雄小鼠经口MTD〉10.0g/kg体重,属实际无毒级物质;骨髓细胞微核试验、小鼠精子畸形试验、Ames试验均为阴性,30d喂养试验中体重和食物利用率、血液学指标均无异常,生化学指标在正常值范围内,主要器官未见病理学改变。结论诺丽果粉无明显毒性。
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| 关 键 词： | 诺丽 毒性 安全性 |
Study on safety of Noni Fruit Powder |
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| LIN Wei-hua,ZHENG Ding-xian,FENG Ding-shan,et al.. Study on safety of Noni Fruit Powder[J]. China Tropical Medicine, 2011, 11(12): 1509-1511 |
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| Authors: | LIN Wei-hua ZHENG Ding-xian FENG Ding-shan et al. |
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| Affiliation: | LIN Wei-hua,ZHENG Ding-xian,FENG Ding-shan,et al.(Hainan Provincial Centor for Desease Prevention and Control,Haikou 570203,China) |
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| Abstract: | Objective Study on toxicity and mutagenecity of Noni fruit powder to assess its safety.Methods Acute Toxicity Test,Bone Marrow Cell Micronucleus Test,Mice Sperm Abnormality Test,Ames test and Thirty Days Feeding Test were performed.Results The MTD in mice was over 10.0g/kg.bw.that showed Noni fruit powder was belong to the nontoxic.Negative results were revealed in Bone Marrow Cell Micronucleus Test and Mice Sperm Abnormality Test as well as in Ames test.Furthermore,in Thirty Feeding Test,nosignificant diff... |
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| Keywords: | Noni Toxicity Safety |
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