| 雌激素与动脉瘤性蛛网膜下腔出血 |
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| 引用本文： | 夏小辉,孙晓川. 雌激素与动脉瘤性蛛网膜下腔出血[J]. 国际脑血管病杂志, 2010, 18(4). DOI: 10.3760/cma.j.issn.1673-4165.2010.04.015 |
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| 作者姓名： | 夏小辉 孙晓川 |
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| 作者单位： | 重庆医科大学附属第一医院神外科,400016 |
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| 摘 要： | 近年来的研究表明,雌激素与动脉瘤性蛛网膜下腔出血关系密切.雌激素可通过多种途径影响颅内动脉瘤发生和发展过程,从而降低动脉瘤破裂发生率.雌激素还能缓解蛛网膜下腔出血后的脑血管痉挛.明确雌激素对动脉瘤性蛛网膜下腔出血的影响和机制,可能发现新的药物作用靶点,预防动脉瘤性蛛网膜下腔出血的发生及其导致的继发性损伤.
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| 关 键 词： | 雌激素 颅内动脉瘤 蛛网膜下腔出血 内皮细胞,血管 |
Estrogen and aneurysmal subarachnoid hemorrhage |
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| XIA Xiao-hui,Sun Xiao-chuan. Estrogen and aneurysmal subarachnoid hemorrhage[J]. International Journal of Cerebrovascular Diseases, 2010, 18(4). DOI: 10.3760/cma.j.issn.1673-4165.2010.04.015 |
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| Authors: | XIA Xiao-hui Sun Xiao-chuan |
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| Abstract: | Studies in recent years have demonstrated that there is close relationship between estrogen and aneurysmal subarachnoid hemorrhage. Estrogen affects the occurrence and development process of intracranial aneurysm through multiple pathways, thereby reducing the incidence of aneurysm rupture. Estrogen also alleviates vasospasm after subarachnoid hemorrhage.Identifying the effects and their mechanisms of estrogen on aneurysmal subarachnoid hemorrhage may find a new drug target to prevent the occurrence of aneurysmal subarachnoid hemorrhage and the secondary injury. |
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| Keywords: | Estrogen Intracranial aneurysm Subarachnoid hemorrhage Endothelium,vascular |
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