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血必净注射液治疗新型冠状病毒肺炎疑似病例24例临床研究
引用本文:李建洪,庞永诚,杨滨枚,毕纳,李刚,龚瑞莹.血必净注射液治疗新型冠状病毒肺炎疑似病例24例临床研究[J].湖南中医杂志,2022,38(1):11-13.
作者姓名:李建洪  庞永诚  杨滨枚  毕纳  李刚  龚瑞莹
作者单位:昆明市中医医院,云南 昆明,650500
基金项目:云南省科技厅中医面上联合专项基金项目(11372110069);云南省昆明市科技保障民生发展计划项目(2019-1-S-25318000001150)。
摘    要:目的:研究血必净注射液治疗新型冠状病毒肺炎(COVID-19)疑似病例的临床疗效.方法:将COVID-19疑似病例48例随机分为治疗组和对照组,每组各24例.对照组采用西医常规治疗,治疗组在对照组的基础上加用血必净注射液治疗.观察比较2组治疗前后体温、心率、C反应蛋白(CRP)、红细胞沉降率(ESR)、肿瘤坏死因子-α...

关 键 词:新型冠状病毒肺炎  疑似病例  中西医结合疗法  血必净注射液

Clinical effect of Xuebijing injection in treatment of patients suspected of coronavirus disease 2019 :An analysis of 24 cases
LI Jianhong,PANG Yongcheng,YANG Binmei,BI Na,LI Gang,GONG Ruiying.Clinical effect of Xuebijing injection in treatment of patients suspected of coronavirus disease 2019 :An analysis of 24 cases[J].Hunan Journal of Traditional Chinese Medicine,2022,38(1):11-13.
Authors:LI Jianhong  PANG Yongcheng  YANG Binmei  BI Na  LI Gang  GONG Ruiying
Institution:(Kunming Municipal Hospital of Traditional Chinese Medicine,Kunming 650500,Yunnan,China)
Abstract:Objective:To investigate the clinical effect of Xuebijing injection in the treatment of patients suspected of coronavirus disease 2019(COVID-19).Methods:A total of 48 patients suspected of COVID-19 were randomly divided into treatment group and control group,with 24 patients in each group.The patients in the control group were given conventional Western medicine treatment,and those in the treatment group were given Xuebijing injection in addition to the treatment in the control group.The two groups were compared in terms of the changes in body temperature,heart rate,C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),tumor necrosis factor-α(TNF-α),and interleukin-6(IL-6)after treatment;clinical outcome was evaluated,and adverse reactions were recorded.Results:There was a significant difference in overall response rate between the treatment group and the control group95.8%(23/24)vs 83.3%(20/24),P<0.05].After treatment,both groups had significant changes in body temperature,heart rate,CRP,ESR,TNF-α,and IL-6,and there were significant differences in these indices between the two groups(P<0.05).No adverse reaction was observed during treatment.Conclusion:Conventional Western medicine treatment combined with Xuebijing injection has a good clinical effect in the treatment of patients suspected of COVID-19 and thus holds promise for clinical application.
Keywords:coronavirus disease 2019  suspected case  integrated traditional Chinese and Western medicine therapy  Xuebijing injection
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