| 自拟健脾益胃汤治疗慢性萎缩性胃炎35例临床观察 |
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| 引用本文： | 颜艳阳. 自拟健脾益胃汤治疗慢性萎缩性胃炎35例临床观察[J]. 湖南中医杂志, 2022, 38(1): 14-16. DOI: 10.16808/j.cnki.issn1003-7705.2022.01.004 |
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| 作者姓名： | 颜艳阳 |
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| 作者单位： | 娄底市中医医院,湖南娄底,417000 |
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| 摘 要： | 目的:观察自拟健脾益胃汤治疗慢性萎缩性胃炎的临床效果.方法:按照随机数字表法将70例慢性萎缩性胃炎患者分为治疗组和对照组,每组各35例.对照组采用常规西药治疗,治疗组在对照组基础上加用自拟健脾益胃汤治疗.治疗结束后,比较2组综合疗效、治疗前后中医证候(胃痛、胃胀、纳差、嗳气、大便不畅)评分、血清炎性因子[肿瘤坏死因子-...
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| 关 键 词： | 慢性萎缩性胃炎 自拟健脾益胃汤 中医证候评分 炎性因子 不良反应 |
Clinical effect of self-made spleen-strengthening and stomach-tonifying decoction in treatment of chronic atrophic gastritis:An analysis of 35 cases |
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| YAN Yanyang. Clinical effect of self-made spleen-strengthening and stomach-tonifying decoction in treatment of chronic atrophic gastritis:An analysis of 35 cases[J]. Hunan Journal of Traditional Chinese Medicine, 2022, 38(1): 14-16. DOI: 10.16808/j.cnki.issn1003-7705.2022.01.004 |
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| Authors: | YAN Yanyang |
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| Affiliation: | (Loudi Municipal Hospital of Traditional Chinese Medicine,Loudi 417000,Hunan,China) |
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| Abstract: | Objective:To investigate the clinical effect of self-made spleen-strengthening and stomach-tonifying decoction in the treatment of chronic atrophic gastritis.Methods:A total of 70 patients with chronic atrophic gastritis were divided into treatment group and control group using a random number table,with 35 patients in each group.The patients in the control group were given conventional Western medicine treatment,and those in the treatment group were given self-made spleen-strengthening and stomach-tonifying decoction in addition to the treatment in the control group.The two groups were compared in terms of overall response,traditional Chinese medicine(TCM)syndrome scores(stomachache,stomach distension,poor appetite,belching,and inhibited defecation),serum levels of inflammatory cytokines(tumor necrosis factor-α,interleukin-1β,and interleukin-8),and incidence rate of adverse reactions.Results:The treatment group had a significantly higher overall response rate than the control group[94.29%(33/35)vs 77.14%(27/35),P<0.05].After treatment,both groups had significant reductions in TCM syndrome scores and the serum levels of the above inflammatory cytokines,and the treatment group had significantly lower indices than the control group(P<0.01 or P<0.05).There was no significant difference in the incidence rate of adverse reactions between the treatment group and the control group[5.71%(2/35)vs 11.43%(4/35),P>0.05].Conclusion:The self-made spleen-strengthening and stomach-tonifying decoction has a good clinical effect in the treatment of chronic atrophic gastritis and can significantly improve symptoms,signs,and inflammatory response with few adverse reactions,and therefore,it holds promise for clinical application. |
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| Keywords: | chronic atrophic gastritis self-made spleen-strengthening and stomach-tonifying decoction traditional Chinese medicine syndrome score inflammatory cytokine adverse reaction |
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