UVB 311 nm tolerance of vitiligo skin increases with skin photo type |
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Authors: | Caron-Schreinemachers Anne-Lou D B Kingswijk Melanie M Bos Jan D Westerhof Wiete |
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Institution: | Netherlands Institute for Pigment Disorders, Amsterdam, The Netherlands. Schreinemachers@amc.uva.nl |
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Abstract: | It is assumed that skin is protected against sunburn by melanin. In patients with vitiligo, there are white patches in the normal pigmented skin. We noticed that there is a difference in burning capacity of these white patches between people with different skin types. With UVB 311 nm lamps, we irradiated both lesional and non-lesional skin with increasing doses in 33 patients with vitiligo, divided into 5 groups according to skin type (II-VI). Twenty-four hours later we assessed the minimal erythema dose and found a correlation between skin type and UV sensitivity in both lesional skin and normal skin. We suggest that there must be a protection mechanism, other than that offered by melanin pigmentation. The antioxidant status may play a role in this phenomenon. |
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