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酪酸梭菌联合消旋卡多曲治疗儿童急性水样性腹泻疗效观察
引用本文:常青,张雷.酪酸梭菌联合消旋卡多曲治疗儿童急性水样性腹泻疗效观察[J].海南医学院学报,2011(11):1582-1584.
作者姓名:常青  张雷
作者单位:无锡市第八人民医院映山河儿童医院,江苏无锡,214002
基金项目:海南医学院科研基金资助学报项目(0020110441)~~
摘    要:目的:观察酪酸梭菌联合消旋卡多曲治疗儿童急性水样性腹泻的临床疗效。方法:将116例腹泻患儿分为两组,每组58例,在调整饮食、液体疗法等综合治疗的基础上,治疗组使用酪酸梭菌联合消旋卡多曲,对照组使用酪酸梭菌联合蒙脱石散,观察比较两组病人的腹泻次数、呕吐和发热缓解情况。结果:治疗24、48、72h治疗组和对照组病人腹泻分别为(6.62±2.31)和(8.32±2.92)次/d(P<0.01)、(3.27±1.25)和(4.82±2.04)次/d(P<0.01)、(1.59±0.76)和(1.86±0.99)次/d(P>0.05),止吐和退热时间分别在用药后(17.52±9.86)和(29.75±13.82)h(P<0.01)、(1.22±0.65)和(1.35±0.97)h(P>0.05)。结论:对比酪酸梭菌联合蒙脱石散,酪酸梭菌联合消旋卡多曲治疗儿童急性水样性腹泻更能缓解前期的腹泻和呕吐症状,但不能更有效地缩短病程,在改善发热方面无优势。

关 键 词:酪酸梭菌  消旋卡多曲  急性水样性腹泻

Effect of combination therapy with clostridium butyricum and racecadotril on acute watery diarrhea in children
CHANG Qing,ZHANG Lei.Effect of combination therapy with clostridium butyricum and racecadotril on acute watery diarrhea in children[J].Journal of Hainan Medical College,2011(11):1582-1584.
Authors:CHANG Qing  ZHANG Lei
Institution:(Yingshanghe Children′s Hospital of the 8th People′s Hospital of Wuxi,Wuxi 214002,China)
Abstract:Objective: To explore the effect of combination therapy with clostridium butyricum and racecadotril on acute watery diarrhea in children.Methods: A total of 116 children with acute watery diarrhea were randomly divided into two groups by half.Besides comprehensive therapy such as diet regulation,fluid therapy,patients in treatment group were treated by combination therapy with clostridium butyricum and racecadotril,while patients in control group were treated by combination therapy of clostridium butyricum ...
Keywords:Clostridium butyricum  Racecadotril  Acute watery diarrhea  
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