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恶性纤维组织细胞瘤及转移瘤3.0T磁共振磷谱研究
引用本文:由长城,朱凯,巴成磊,关国发,闫景龙,徐公平,张志鹏,赵伟. 恶性纤维组织细胞瘤及转移瘤3.0T磁共振磷谱研究[J]. 实用诊断与治疗杂志, 2011, 25(10)
作者姓名:由长城  朱凯  巴成磊  关国发  闫景龙  徐公平  张志鹏  赵伟
作者单位:1. 哈尔滨医科大学附属第一医院骨外四科,哈尔滨市,150001
2. 哈尔滨市儿童医院影像科 150010
3. 青岛市中心医院骨外科,山东省,266042
摘    要:目的探讨3.0T磁共振对恶性纤维组织细胞瘤及转移瘤的成像特征,并分析其相应磁共振31P波谱特点。方法对10名健康成年人(对照组),6例恶性纤维组织细胞瘤患者(恶纤组)及8例转移瘤患者(转移瘤组)行3.0T磁共振常规扫描及单体素磷谱检查,分析其影像特征及代谢产物特点。结果与对照组比较,恶纤组磷酸肌酸(phosphocreatine,PCr)面积、总三磷酸腺苷(adenosine triphosphate,ATP)、PCr峰高、PCr/无机磷(inorganicphosphorus,Pi)下降,磷酸单酯(phosphomonoesterase,PME)峰高、pH值、PME/三磷酸核苷(nucleoside triphosphate,NTP)、-βATP/Pi升高(P<0.05);转移瘤组PCr面积、PCr峰高、PCr/Pi、PCr/NTP、PCr/-βATP下降,pH值、PME/NTP、磷酸二酯/NTP升高(P<0.05);恶纤组及转移瘤组各代谢物及其相关比值比较,差异均无统计学意义(P>0.05)。结论 3.0T磁共振对恶性纤维组织细胞及转移瘤显像清晰,磷谱特征可帮助分析其肿块组织的生化信息。

关 键 词:3.0T磁共振磷谱  恶性纤维组织细胞瘤  转移瘤  

Phosphorus magnetic resonance spectroscopy at 3.0 Telsa in malignant fibrous histiocytoma and metastatic tumor
YOU Chang-cheng,ZHU Kai,BA Cheng-lei,GUAN Guo-fa,YAN Jing-long,XU Gong-ping,ZHANG Zhi-peng,ZHAO Wei. Phosphorus magnetic resonance spectroscopy at 3.0 Telsa in malignant fibrous histiocytoma and metastatic tumor[J]. Journal of Practical Diagnosis and Therapy, 2011, 25(10)
Authors:YOU Chang-cheng  ZHU Kai  BA Cheng-lei  GUAN Guo-fa  YAN Jing-long  XU Gong-ping  ZHANG Zhi-peng  ZHAO Wei
Affiliation:YOU Chang-cheng1),ZHU Kai2),BA Cheng-lei3),GUAN Guo-fa1),YAN Jing-long1),XU Gong-ping1),ZHANG Zhi-peng1),ZHAO Wei1)1) Department of Orthopedics,the First Affiliated Hospital to Harbin Medical University,Harbin 150001,China,2) Department of Radialogy,Harbin Children's Hospital,Harbin 150010,3)Department of Orthopedics,Qingdao Center Hospital,Qingdao 266042
Abstract:Objective To investigate the phosphorus magnetic resonance spectroscopy at 3.0 Telsa imaging features of malignant fibrous histiocytoma and metastatic tumors and to analyze the corresponding 31P magnetic resonance spectroscopy features.Methods Phosphorus magnetic resonance spectroscopy at 3.0 Telsa and single voxel phosphorus spectrum examination were performed in 10 healthy adults,6 cases of malignant fibrous histiocytoma and 8 cases of metastases to analyze the imaging features and metabolites characteris...
Keywords:Phosphorus magnetic resonance spectroscopy at 3.0 Telsa  malignant fibrous histiocytoma  metastatic tumor  
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