| [~3H]盐酸小檗胺的吸收、分布及排泄 |
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| 引用本文： | 杨帆,金少宇,李亦秀,李文汉,仪明光. [~3H]盐酸小檗胺的吸收、分布及排泄[J]. 哈尔滨医科大学学报, 1988, 0(2) |
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| 作者姓名： | 杨帆 金少宇 李亦秀 李文汉 仪明光 |
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| 作者单位： | 哈尔滨医科大学药理学教研室(杨帆，金少宇，李亦秀，李文汉)，中国科学院原子能研究所(仪明光) |
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| 摘 要： | 给小鼠口服氚标记的盐酸小檗胺后5分钟,血中即可测出放射性,半小时达高峰。血中浓度-时间曲线符合二房室开放模型。组织分布以肝脏为最高,依次是肾、肺、脾、心和脑。以粪便排泄为主。
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| 关 键 词： | [~3H]盐酸小檗胺 吸收 分布 排泄 |
Absorption, Distribution and Elimination of Tritium Labeled Berbamine |
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| Yang Fan et al. Absorption, Distribution and Elimination of Tritium Labeled Berbamine[J]. Journal of Harbin Medical University, 1988, 0(2) |
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| Authors: | Yang Fan et al |
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| Affiliation: | Yang Fan et al |
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| Abstract: | After tritium labeled berbamine was given by mouth in mice, the radioactivitv (?) be defected in blood in five minutes. The peak was in half an hour. The Concentration-Time Curve was consistent with open two-compartment model. Distribution of the radioactivity in the liver was the highest, followed by the kidney, the lung, the spleen, the heart and the brain. The drug was chiefly eliminated from the feces. |
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| Keywords: | Tritium labeled berbamine Absorption Distribution Elimination |
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