Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice |
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| Authors: | Brodkin Edward S Hagemann Andrea Nemetski Sondra Maureen Silver Lee M |
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| Affiliation: | Department of Psychiatry, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Room 111, Philadelphia, PA 19104-6140, USA. ebrodkin@mail.med.upenn.edu |
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| Abstract: | Little is known about the genetics of social approach-avoidance behaviors. We measured social approach-avoidance of prepubescent female C57BL/6J, DBA/2J, FVB/NJ, AKR/J, A/J, and BALB/cJ mice towards prepubescent DBA/2J female mice. C57BL/6J mice showed the greatest predominance of approach, while BALB/cJ mice showed the greatest predominance of avoidance. Thus, this phenotype is affected by spontaneous genetic variation in mice and can be measured in an assay useful for future neurogenetic studies. |
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