| 单向释药双层缓释贴膜治疗口腔溃疡的疗效观察 |
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| 引用本文： | 刘国勤,马晓蓬,宋培智,刘海英,侯惠民,贺芬. 单向释药双层缓释贴膜治疗口腔溃疡的疗效观察[J]. 第二军医大学学报, 2002, 23(6): 667-668 |
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| 作者姓名： | 刘国勤 马晓蓬 宋培智 刘海英 侯惠民 贺芬 |
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| 作者单位： | 1. 解放军第411医院海军口腔专科中心,上海,200081
2. 上海医药工业研究院 |
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| 摘 要： | 目的：考察醋酸地塞米松双层缓释贴膜对口腔溃疡的临床疗效。方法：随机收集1998年6月至2001年9月复发性口疮344例（含对照组114例），扁平苔藓193例（含对照组68例），放射性粘膜炎130例（含对照组49例），共667例（含对照组231例），采用随机单盲法以酸地塞米松双层贴膜A（治疗组）和安慰片B（对照组）进行临床验证。结果：治疗组总有效率为96．1％，与对照组比较有极显著性差异（P＜0．01），无1例出现不良反应。结论：该贴膜用于治疗口腔溃疡，临床疗效非常显著。
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| 关 键 词： | 单向释药 双层缓释贴膜 口腔溃疡 疗效观察 |
| 文章编号： | 0258-879X(2002)06-0667-02 |
| 修稿时间： | 2002-03-01 |
Therapeutic effects of one-way sustained-release bistratal drug-film for oral ulcer |
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| LIU Guo Qin ,MA Xiao Peng ,SONG Pei Zhi ,LIU Hai Ying ,HOU Hui Min ,HE Fen. Therapeutic effects of one-way sustained-release bistratal drug-film for oral ulcer[J]. Former Academic Journal of Second Military Medical University, 2002, 23(6): 667-668 |
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| Authors: | LIU Guo Qin MA Xiao Peng SONG Pei Zhi LIU Hai Ying HOU Hui Min HE Fen |
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| Affiliation: | LIU Guo Qin 1,MA Xiao Peng 1,SONG Pei Zhi 1,LIU Hai Ying 1,HOU Hui Min 2,HE Fen 2 |
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| Abstract: | Objective:To evaluate the therapeutic effect of sustained release bistratal drus film containing dexamethasoni acetate (DA) in treatment of oral ulcer. Methods:Totally 667(231 cases as control group) patients (June 1998 to September 2001) with recurrent aphthous ulcer, lichen planus, radio catarrh were studied randomly to evaluate the therapeatic effect in a single blind random way. Results:The effective rates of treated group and control group were 96.1% and 28.6%, respectively, and the difference between 2 groups was significant ( P <0.01). None of 667 cases had side effects. Conclusion:DA sustained release bistratal drug film is a new medicine for treating oral ulcer. |
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| Keywords: | stomatitis aphthous dexamethasoni acetate drug film delayed action preparations |
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