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心钠素治疗糖尿病肾病肾功能不全的临床研究
引用本文:赵伟河,田永红,袁芳,史殿勋,刘建平. 心钠素治疗糖尿病肾病肾功能不全的临床研究[J]. 中国民康医学, 2005, 17(1): 8-9
作者姓名:赵伟河  田永红  袁芳  史殿勋  刘建平
作者单位:河南第一荣康医院,河南,新乡,453003
摘    要:目的:探讨糖尿病肾病(DN)肾功能不全的治疗方法。方法:对15例DN肾功能不全病人用心钠素(ANP)治疗,84mg,bid肌肉注射,连用14天,并设酚妥拉明+多巴胺+速尿治疗组做对照,观察治疗前后两组病人血清尿素氮(BUN)和血清肌酐(CR)及血压改变情况,进行统计学处理。结果:两组病人治疗后肾功能都有明显改善,统计学有显著性,P<0.05或更低;心钠素组CR下降较对照组更明显,P<0.001。结论:心钠素是一种有效的DN肾功能不全治疗药物。

关 键 词:心钠素 糖尿病肾病 肾功能不全
文章编号:0369(2005)01-0008-02
修稿时间:2004-06-28

Clinical studyof atrialnatriuretic peptide on treating renal failure caused by Diabetic Nephropathy
ZHAO Wei-he,TIAN Yong-hong,YUAN Fang,et al. Clinical studyof atrialnatriuretic peptide on treating renal failure caused by Diabetic Nephropathy[J]. medical journal of chinese peoples health, 2005, 17(1): 8-9
Authors:ZHAO Wei-he  TIAN Yong-hong  YUAN Fang  et al
Abstract:Objective:To study the effective of atrial natriuretic peptide(ANP) on treating renal failure caused by diabetic nephropathy . Methods: 30 patients with renal failure caused by diabetic nephropathy divided into two groups - ANP group and the control. the first group was treated by ANP for fourteen days; the control groups was treated by phentolamine.doparnine and katlex.Observation the levels of blood urianitrogen(BUN),serum creatinine(CR) and blood pressure after treated and analyses.Result:The BUN and CR levels of both two groups after treated were obviously dereased than before; the CR level in ANP group was significantly lower than the control.Conclusion: ANP is a effect drug on treating renal failure caused by DN.
Keywords:atrial natriuretic peptide  diabetic nephropathy  renalfailure
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