High-Porosity expanded polytetrafluoroethylene grafts with omentum wrap for portal vein replacement: Intermediate results |
| |
Authors: | Toshiya Nishibe Hideki Ohkashiwa Yoshiaki Satoh Nozomu Iwashiro Satoshi Watanabe Hiroyuki Katoh Yasuhiro Okuda Tatsuzo Tanabe |
| |
Affiliation: | (1) Second Department of Surgery, Hokkaido University School of Medicine, K14, N5, Kita-ku, 060 Sapporo, Japan;(2) Vascular Graft Research Center Ltd., 1-16-13 Kita-kasai, Edogawd-ku, 134 Tokyo, Japan;(3) Sapporo General Hospital of Nippon Telephone and Telegraph Co., Ltd., M1, N14, Chuo-ku, 060 Sapporo, Japan |
| |
Abstract: | The purpose of this study was to examine the intermediate (6-month) patency and healing characteristics of high-porosity expanded polytetrafluoroethylene (ePTFE) grafts with and without omentum wrap in a dog portal vein replacement model, compared with short-term (1-month) results. The grafts, either wrapped by omentum or not, were placed as portal vein replacements in 22 mongrel dogs. After 1 and 6 months, the grafts were retrieved and examined for patency and subjected to pathology study. Although the short-term patency rate in all grafts was 100%, regardless of the presence or absence of omentum wrap, the intermediate patency of high-porosity ePTFE without omentum wrap was very poor (20%). On the other hand, high-porosity ePTFE with omentum wrap had an intermediate patency rate of 100%. At 6 months, the high-porosity ePTFE grafts with omentum wrap were completely healed. The pseudointima was entirely replaced by thin fibrous tissue, with complete endothelial-like cell coverage throughout the graft. This result suggests that high-porosity ePTFE with omentum wrap could be a suitable prosthetic alternative to autogenous vein graft in portal vein reconstruction. |
| |
Keywords: | high-porosity expanded polytetrafluoroethylene grafts portal vein replacement omental wrap |
本文献已被 SpringerLink 等数据库收录! |
|