天然药物靶向给药系统的研究

采用新型药物载体使天然药物具有靶向作用是近年来药剂学的研究热点之一。综述脂质体、纳米粒、微球、微乳、药质体等新型载体在天然药物靶向给药系统研究中的应用,并介绍膜融合脂质体、纳米脂质载体、药脂结合物纳米粒以及分泌颗粒类似物等几种新型靶向给药系统的药物载体。

Advances in the Research on Target Drug Systems of Natural Drugs

The research on target drug systems of natural drugs is one of the highlights of pharmaceutics recently. The applications of several drug delivery carriers such as liposmes, nanoparticles, microspheres, microemulsions, pharmacosomes to target drug systems of natural drugs were reviewed as well as some novel drug delivery carriers, such as fusogenic liposomes, nanostructured lipid carriers, lipid drug conjugate nanoparticles and mimic of the secretory granule were introduced.