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氨磷汀副反应的观察和预防
引用本文:崔慧娟,李佩文,卞美璐,孙晓菲,沈铿,吴明,胡小电,吴世凯,刘淑俊,邸立军,张树才,杨新杰. 氨磷汀副反应的观察和预防[J]. 肿瘤学杂志, 2002, 8(1): 19-21
作者姓名:崔慧娟  李佩文  卞美璐  孙晓菲  沈铿  吴明  胡小电  吴世凯  刘淑俊  邸立军  张树才  杨新杰
作者单位:1. 中日友好医院,北京 100029
2. 中山医科大学附属肿瘤医院,广东广州510060
3. 北京医科大学临床肿瘤医院,北京
4. 解放军307医院,北京,100000
5. 北京市结核病胸部肿瘤研究所,北京,101149
摘    要:[目的]观察氨磷汀的毒副反应。[方法]193例恶性肿瘤患者 ,随机分为两组 ,观察组化疗前应用氨磷汀 ,对照组单用化疗。[结果]观察组出现轻度一过性血压下降 ,未到低血压程度 ;恶心、呕吐两组无明显差异 ;观察组14.7%患者出现低血钙 ,14天时恢复正常 ,以上反应均可预防。[结论]氨磷汀有一定副反应 ,可以预防 ,患者可以耐受。

关 键 词:氨磷汀  副反应  预防
文章编号:1671-170X(2002)01-0019-03
修稿时间:2001-10-29

The Study on the Side Effects of Amifostine and its Preventive Measures
CUI Hui juan,LI Pei wen,BIAN Mei lu,et al.. The Study on the Side Effects of Amifostine and its Preventive Measures[J]. Journal of Chinese Oncology, 2002, 8(1): 19-21
Authors:CUI Hui juan  LI Pei wen  BIAN Mei lu  et al.
Abstract:To investigate the side effects and prophylaxis of Amifostine. One hundred and ninty three patients with malignant tumor were divided into treatment group treated by amifostine before chemotherapy and control group which treated by chemotherapy alone. A light and temporality hypotension occurred in treatment group, but the patient blood pressure was normal;there were no significant difference in nause and vomiting between two groups;14.7% patients in treatment group had hypocalcemia and got to normal in 14 days. These side effects could be prevented before hand.[Conclusion] Amifostine has some side effects which can be prevented and are tolerable.
Keywords:amifostine  side effects  prevention  
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