| 高效液相色谱法测定心舒宝胶囊中芍药苷含量 |
| |
| 引用本文： | 贾乐陶,王慧,陈进,魏福荣,张宏业.高效液相色谱法测定心舒宝胶囊中芍药苷含量[J].中国药业,2008,17(2):36-37. |
| |
| 作者姓名： | 贾乐陶 王慧 陈进 魏福荣 张宏业 |
| |
| 作者单位： | 1. 江苏省镇江市第一人民医院,江苏,镇江,212001
2. 江苏吉贝尔药业有限公司,江苏,镇江,212009 |
| |
| 摘 要： | 目的采用高效液相色谱（HPLC）法测定心舒宝胶囊中芍药苷的含量。方法 C18色谱柱，流动相为乙腈-0．4％磷酸溶液（15：85），流速1mL／min，柱温30℃，检测波长230nm。结果芍药苷质量浓度在24．84-372.6μg／mL范围内与峰面积积分值线性关系良好。平均回收率为98．7％，RSD为1．12％（n=9）。结论方法简便可行、结果准确、重现性好，可用于该制剂的质量控制。
|
| 关 键 词： | 心舒宝胶囊 芍药苷 高效液相色谱法 |
| 文章编号： | 1006-4931(2008)02-0036-02 |
| 修稿时间： | 2007年4月3日 |
Determination of Paeoniflorin in Xinshubao Capsule by HPLC |
| |
| Jia Letao,Wang Hui,Chen Jin,Wei Furong,Zhang Hongye.Determination of Paeoniflorin in Xinshubao Capsule by HPLC[J].China Pharmaceuticals,2008,17(2):36-37. |
| |
| Authors: | Jia Letao Wang Hui Chen Jin Wei Furong Zhang Hongye |
| |
| Institution: | Jia Letao, Wang Hui, Chen Jin, Wei Furong, Zhang Hongye ( 1. Zhenjiang No. 1 People＇ s Hospital, Zhenjiang, Jiangsu, China 212001; 2. Jiangsu Jibeier Pharmaceutical Co., Ltd, Zhenjiang, Jiangsu, China 212009) |
| |
| Abstract: | Objective To establish HPLC method for the determination of paeoniflorin in Xinshubao Capsules. Methods The paeoniflofin was determinated by HPLC. The samples were separated by C18 column with the mobile phase of CH3CN- 0. 1% H3PO4（15：85）, the wavelength of detection was at 230 nm. Results Paeoniflorin showed a good linear relationship within the range of 24.84 - 372. 6 μg/mL（ r = 0. 999 9） and the average recovery rate was 98.7%, RSD = 1.12%. Conclusion The method is accurate with good repeatability. It can be used for the quality control of Xinshubao Capsule. |
| |
| Keywords: | Xinshubao Capsule paeoniflorin HPLC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
