| 2004～2008年下呼吸道医院感染病原菌分布及耐药性分析 |
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| 引用本文： | 金晨慈,蒋欢欢,蒋龙翔. 2004～2008年下呼吸道医院感染病原菌分布及耐药性分析[J]. 中华医院感染学杂志, 2010, 20(7) |
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| 作者姓名： | 金晨慈 蒋欢欢 蒋龙翔 |
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| 作者单位： | 温州市中西医结合医院呼吸科,浙江,温州,325000 |
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| 摘 要： | 目的调查医院获得性下呼吸道感染病原菌分布及其耐药性情况,为临床合理使用抗菌药物提供参考。方法采用回顾性调查的方法,对医院2004年1月~2008年12月发生下呼吸道医院感染的患者呼吸道分泌物进行细菌培养和药敏试验。结果共分离到598株病原菌,其中革兰阴性菌461株(77.1%),主要为铜绿假单胞菌167株(27.9%)、肺炎克雷伯菌85株(14.2%)、鲍氏不动杆菌64株(10.7%);革兰阳性菌137株(22.9%),以金黄色葡萄球菌95株(15.9%)和凝固酶阴性葡萄球菌32株(5.4%)为主;上述常见细菌,均表现出了极高的多药耐药性,其中铜绿假单胞菌和鲍氏不动杆菌对头孢哌酮/舒巴坦仍保持了较高的敏感性,而肠杆菌科细菌则对头孢哌酮/舒巴坦、哌拉西林/他唑巴坦、亚胺培南耐药率较低;金黄色葡萄球菌和凝固酶阴性葡萄球菌尚未发现对万古霉素耐药。结论医院获得性下呼吸道感染临床分离病原以革兰阴性杆菌为主,感染菌的耐药性高,临床上及时掌握医院病原菌变化规律及耐药情况,可以更有效地预防和治疗下呼吸道获得性感染。
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| 关 键 词： | 下呼吸道感染 病原菌 耐药性 抗菌药物 |
Clinical Bacterial Distribution and Analysis of Drug Resistance in Lower Respiratory Tract Nosocomial Infection From 2004 to 2008 |
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| JIN Chen-ci,JIANG Huan-huan,JIANG Long-xiang. Clinical Bacterial Distribution and Analysis of Drug Resistance in Lower Respiratory Tract Nosocomial Infection From 2004 to 2008[J]. Chinese Journal of Nosocomiology, 2010, 20(7) |
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| Authors: | JIN Chen-ci JIANG Huan-huan JIANG Long-xiang |
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| Affiliation: | JIN Chen-ci,JIANG Huan-huan,JIANG Long-xiang (Wenzhou Integrated TCM & Western Medicine Hospital,Wenzhou,Zhejiang 325000,China) |
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| Abstract: | OBJECTIVE To analyze the bacterial distribution and drug resistance in lower respiratory tract nosocomial infection(NI) and ofter the reference of clinical application.METHODS The qualified sputum samples for patients who were admitted from Jan 2006 to Dec 2007 was cultured and analyzed.RESULTS Totally 461 strains of bacteria were isolated.The dominant were Gram-negative bacilli(77.1%),among which Pseudomonas aeruginosaaccouted for 27.9%,Klebsiella pneumoniae14.2%,Acinetobacter baumannii10.7%,Proteus mirabi... |
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| Keywords: | Lower respiratory t ract infection Bacteria Drug resistance Antibiotics |
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