Vascular Complications in Renal Transplantation: A Single-Center Experience in 1367 Renal Transplantations and Review of the Literature |
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| Authors: | D Dimitroulis J Bokos G Zavos N Nikiteas NP Karidis P Katsaronis A Kostakis |
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| Institution: | 1. Second Propaedeutic Department of Surgery, University of Athens, Medical School, Athens, Greece;2. Transplantation Unit, Laiko General Hospital, Athens, Greece;1. Division of Transplantation Surgery, Department of Surgery and William von Liebig Transplant Center, Mayo Clinic, Rochester, MN;2. Division of Biostatistics, Mayo Clinic, Rochester, MN;3. Department of Urology, Mayo Clinic, Rochester, MN;1. Renal Transplant Unit, Clinics Hospital, State University of Campinas, Campinas, São Paulo, Brazil;2. Division of Urology, Department of Surgery, State University of Campinas, Campinas, São Paulo, Brazil;3. Division of Nephrology, Department of Medicine, State University of Campinas, Campinas, São Paulo, Brazil;1. Department of Infectious Diseases and Clinical Microbiology, Ankara University Faculty of Medicine, Ankara, Turkey;2. Department of Nephrology, Ankara University Faculty of Medicine, Ankara, Turkey;3. Department of Internal Medicine, Ankara University Faculty of Medicine, Ankara, Turkey;4. Department of General Surgery, Ankara University Faculty of Medicine, Ankara, Turkey;1. Department of Surgery, Division of Renal and Pancreas Transplant, Saint Barnabas Medical Center, Livingston, New Jersey, USA;2. Department of Surgery, Division of Vascular Surgery, Saint Barnabas Medical Center, Livingston, New Jersey, USA;3. Department of Urology, Saint Barnabas Medical Center, Livingston, New Jersey, USA |
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| Abstract: | Renal transplantation is the treatment of choice for end-stage renal disease. Vascular complications in renal transplantation are not uncommon and may often lead to allograft loss. The most common vascular complications are transplant renal artery stenosis, transplant renal artery thrombosis, transplant renal vein thrombosis, biopsy-induced vascular injuries, pseudoaneurysm formation, and hematomas. Transplant renal artery and vein thrombosis have an early onset and a dramatic clinical manifestation and usually lead to allograft loss. In contrast, transplant renal artery stenosis has better treatment possibilities, whereas the rest do not occur so often. In our institution, 1367 renal transplantations were performed from September 1980 to April 2005. During this period, we encountered 38 major vascular complications leading to graft loss and 19 transplant renal artery stenoses with successful treatment in the majority of cases. According to these data, we can conclude that renal transplantation is a safe therapeutic procedure for renal failure. |
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