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| 山芝麻含药血清对HepG2.2.15细胞HBV复制的抑制作用 | |
| 引用本文： | 黄权芳,韦刚,杨辉,林兴,张士军,黄仁彬. 山芝麻含药血清对HepG2.2.15细胞HBV复制的抑制作用[J]. 时珍国医国药, 2012, 23(7): 1849-1850 |
| 作者姓名： | 黄权芳 韦刚 杨辉 林兴 张士军 黄仁彬 |
| 作者单位： | 1. 广西中医学院第一附属医院,广西南宁,530023 2. 广西分析测试研究中心,广西南宁,530022 3. 广西医科大学,广西南宁,530021 |
| 基金项目： | 广西壮族自治区教育厅自然科学基金 |
| 摘 要： | 目的观察山芝麻体外抗乙型肝炎病毒(HBV)的作用。方法采用血清药理学方法,在HBV的体外细胞培养系统中(2.2.15细胞)进行山芝麻抗HBV作用观察。结果山芝麻含药血清在HepG2.2.15细胞培养中可有效地抑制细胞HBV DNA的复制,其作用呈明显的量效和时效反应关系。结论山芝麻在体外能明显抑制HBV。 |
| 关 键 词： | 山芝麻 乙型肝炎病毒 HepG2.2.15细胞 |
The Inhibitory Effect of the Serum Containing Helicteres angustifolia on HBV DNA in the HepG2.2.15 Cells |
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| HUANG Quan-fang , WEI Gang , YANG Hui , LIN Xing , ZHANG Shi-jun , HUANG Ren-bin. The Inhibitory Effect of the Serum Containing Helicteres angustifolia on HBV DNA in the HepG2.2.15 Cells[J]. Lishizhen Medicine and Materia Medica Research, 2012, 23(7): 1849-1850 | |
| Authors: | HUANG Quan-fang WEI Gang YANG Hui LIN Xing ZHANG Shi-jun HUANG Ren-bin |
| Affiliation: | 1.The First Affiliated Hospital of Guangxi Traditional Chinese Medical University,Nanning,530023,China;2.Guangxi Center for Analysis and Test Research,Nanning 530022,China;3.Guangxi Medical University,Nanning 530021,China) |
| Abstract: | Objective To study anti-HBV activity of Helicteres angustifolia in vitro.Methods The HBV in vitro cell culture system(HepG2.2.15 cell) was used for examining the anti-HBV activity of Helicteres angustifolia with Serum-pharmacology.Results The serum containing Helicteres angustifolia could decrease the HBV DNA level in HepG2.2.15 cell,and its inhibitory effects were dose-and time-dependent.Conclusion Helicteres angustifolia can inhibit HBV DNA in vitro significantly. |
| Keywords: | Helicteres angustifolia HBV HepG2.2.15 cell |
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