金螵汤治疗早期糖尿病肾病临床研究

目的：探讨中西医结合治疗早期糖尿病肾病的疗效。方法：120例患者按随机原则分为治疗组和对照组（各60例）。两组患者均在基础治疗的同时采用西药有效控制血糖水平,治疗组在此基础上加用金螵汤。两组均治疗6个月,并同时观察两组治疗前后症状、体征及实验室相关指标。结果：总有效率治疗组为91.7%,对照组为58.3%,两组比较有显著性差异（P〈0.01）。24h尿蛋白排泄量,血糖,尿微量白蛋白,血、尿β2-MG,血脂,血液流变学等指标治疗组治疗后均较治疗前有显著改善（P〈0.05或P〈0.01）。结论：中西医结合治疗早期糖尿病肾病疗效明显优于单纯西药治疗。

Clinical Research on Jinpiao Decoction in Treating Patients with Early Diabetic Nephropathy

Objective：To observe the effect of treatment combining traditional Chinese and western medicine on early diabetic nephropathy.Methods：120 patients with early diabetic nephropathy were randomly divided into two groups,the treatment group（n=60）and the control group（n=60）.2 groups of patients are in the foundation treatment at the same time effectively control blood sugar levels by western medicine,treatment group based on it and added the Jinpiao Decoction.2 group were treated,and six months after treatment and observed 2 groups of symptoms,physical signs and laboratory related indicators.Results：The total effective rate of treatment group is 91.7% and control group is 58.3%,two groups with significant difference（P〈0.01）.24h urine protein excretion,blood glucose,microalbuminuria,blood and urine beta 2-MG,blood fat,hemorheology indices such as the treatment group were more treatment after treatment before improed significantly（P〈0.05 or P〈0.01）.Conclusion：Treatment combining traditional Chinese and western medicine on early diabetic nephropathy is better than pure western medicine.