| 海洋放线菌P19—19化学成分研究 |
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| 引用本文： | 魏雅楠,才谦,裴月湖.海洋放线菌P19—19化学成分研究[J].辽宁中医学院学报,2011(9):47-48. |
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| 作者姓名： | 魏雅楠 才谦 裴月湖 |
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| 作者单位： | [1]辽宁中医药大学,辽宁大连116600 [2]沈阳药科大学中药学院,辽宁沈阳110016 |
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| 基金项目： | 国家高技术研究发展计划（863计划）支持项目（2007AA092413） |
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| 摘 要： | 目的：对海洋放线菌P19-19的化学成分进行研究。方法：采用硅胶柱色谱、凝胶以及HPLC等方法进行分离纯化,并根据理化性质和光谱数据确定其结构。结果：分离得到7个化合物,分别鉴定为环苯丙-酪氨酸二肽（1）、对羟基苯乙醇（2）、丁二酸（3）、2H-1,3-Thiazine-2,4（3H）-dione（4）、尿嘧啶（5）、对羟基苯乙酸甲酯（6）、2-甲氧基-4’-羟基苯丙酸（7）。
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| 关 键 词： | 海洋放线菌 结构鉴定 柱色谱 波谱解析 |
Chemical Constituents from the Marine Actinomycetes P19-19 |
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| WEI Ya-nan,CAI Qian,PEI Yue-hu.Chemical Constituents from the Marine Actinomycetes P19-19[J].Journal of Liaoning College of Traditional Chinese Medicine,2011(9):47-48. |
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| Authors: | WEI Ya-nan CAI Qian PEI Yue-hu |
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| Institution: | 1.Liaoning University of Traditional Chinese Medicine, Dalian 116600, Liaoning, China; 2.School of Traditional Chinese Masica, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China ) |
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| Abstract: | Objective：To study chemical constituents from the marine actinomycetes P19-19.Methods：The compounds from the ethyl acetate extracts were isolated by silica gel column,Sephadex LH-20 column and HPLC,and their structures were identified by 1H-NMR,13C-NMR and comparison of chemical and physical data with authentic samples reported in literatures.Results：Seven compounds were isolated and identified as 2,5-piperazinedione,3-（4-hydroxyphenyl）methyl-6-（phenylmethyl）]（1）,Benzeneethanol,4-hydroxy（2）,succinic acid（3）,2H-1,3-Thiazine-2,4（3H）-dione（4）,uracil（5）,Ethylidene,1-（4-hydroxyphenyl）-2-methoxy-2-oxo（6）,3-（4′-hydroxyphenyl）-2-methoxypropanoic acid（7）. |
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| Keywords: | marine actinomycetes structural identification column chromatography spectroscopy analysis |
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