小儿血液病部分脾栓塞治疗的临床研究

目的　探讨部分脾栓塞治疗小儿血液病的临床疗效、免疫功能及并发症。方法　采用 Seldinger` s法 ,行部分脾栓塞 (Partial Splenic Embolization,PSE)治疗小儿慢性特发性血小板减少性紫癜 (Idiopathic Thrombocytopenic Purpura,ITP)、先天性红细胞丙酮酸激酶缺陷症及脾功能亢进共 13例 ,选用明胶海绵颗粒作为栓塞剂 ,栓塞范围控制在 6 0 %～ 80 %之间。结果　患儿在术后 2周血小板升至正常 ,临床症状改善 ,栓塞前后免疫球蛋白无明显变化 ,无严重并发症。结论　 PSE治疗部分小儿血液病例可保留小儿的免疫功能 ,取得满意疗效 ,值得临床推广。

Clinical Study of Partial Splenic Embolization in the Treatment of Pediatric Hemopathy

Objective To explore the clinical effects of partial splenic embolization (PSE) in the treatment of some kinds of pediatric hemopathy,immune function and complications Methods 13 cases of pediatric chronic ITP,congenital erythrocyte pyruvate kinase deficiency and hypersplenism were treated by PSE by means of Seldinger`s method,gelfoam particle was used as embolic agent,embolic area was keeped within 60% to 80% Results After 2 weeks of postoperation,patients platelet count raised to normal,and clinical symptoms improved,there were no significantly changes after embolization as compared with that before embolization,no severe complications Conclusions PSE can reserve patients immune function when it used to treat some kinds of pediatric hemopathy,and have satisfactory clinical effects,may be used widely in clinical practive