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A transdiagnostic evaluation of contrast avoidance across generalized anxiety disorder,major depressive disorder,and social anxiety disorder
Affiliation:1. Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai 200030, China;2. Nathan Kline Institute for Psychiatric Research, New York, USA;3. Department of Psychiatry, NYU Medical School, New York, USA;4. School of Government, Shanghai University of Political Science and Law, Shanghai, China;5. Suzhou Guangji Hospital, Suzhou, China;6. CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Chinese Academy of Science, China;7. Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, China;8. Institute of Psychology and Behavioral Science, Shanghai Jiao Tong University, Shanghai, China
Abstract:BackgroundThe contrast avoidance model (CAM) proposes that persons with generalized anxiety disorder (GAD) are sensitive to sharp increases in negative emotion or decreases in positive emotion (i.e., negative emotional contrasts; NEC) and use worry to avoid NEC. Sensitivity to and avoidance of NEC could also be a shared feature of major depressive disorder (MDD) and social anxiety disorder (SAD).MethodsIn a large college sample (N = 1409), we used receiver operating characteristics analysis to examine the accuracy of a measure of emotional contrast avoidance in detecting probable GAD, MDD, and SAD.ResultsParticipants with probable GAD, MDD, and SAD all reported higher levels of contrast avoidance than participants without the disorder (Cohen’s d = 1.32, 1.62 and 1.53, respectively). Area under the curve, a measure of predictive accuracy, was .81, .87, and .83 for predicting probable GAD, MDD, and SAD, respectively. A cutoff score of 48.5 optimized predictive accuracy for probable GAD and SAD, and 50.5 optimized accuracy for probable MDD.ConclusionA measure of emotional contrast avoidance demonstrated excellent ability to predict probable GAD, MDD, and SAD. Sensitivity to and avoidance of NEC appears to be a transdiagnostic feature of these disorders.
Keywords:Generalized anxiety disorder  Major depressive disorder  Social anxiety disorder  Transdiagnostic  Contrast avoidance  NEC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0035"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  negative emotional contrast  AUC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0045"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  area under the curve  GAD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0055"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  generalized anxiety disorder  MDD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0065"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  major depressive disorder  SAD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0075"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  social anxiety disorder  CAM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0085"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  contrast avoidance model  PEC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0095"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  positive emotional contrast  CAQ-GE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0105"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Contrast Avoidance Questionnaire-General Emotion scale  GAQ-IV"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0115"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Generalized Anxiety Disorder Questionnaire-IV  BDI-II"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0125"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Beck Depression Inventory-II  SPDQ"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0135"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Social Phobia Diagnostic Questionnaire  ROC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0145"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  receiver operating characteristic  PPV"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0155"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  positive predictive value  NPV"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0165"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  negative predictive value  CAQ-W"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  key0175"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Contrast Avoidance-Worry scale
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