Comparison of oral health characteristics in pediatric cancer and cancer free patients: A multicenter study |
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| Affiliation: | 1. Pediatric Dentistry Department, Saint Joseph University, Beirut, Lebanon;2. Division of Orthodontics and Dentofacial Orthopedics, Department of Dentofacial Medicine, American University of Beirut Medical Center, Beirut, Lebanon;3. Resident in Internal Medicine, Hotel Dieu de France Hospital, Saint Joseph University, Beirut, Lebanon;4. Pediatric Dentistry Department, Faculty of Dental Medicine, Saint Joseph University, Beirut, Lebanon;5. Department of Dentofacial Medicine, American University of Beirut Medical Center, Beirut, Lebanon;1. School of Dentistry, University of Ribeirão Preto (UNAERP), Avenida Costábile Romano 2201, Ribeirão Preto, São Paulo, 14096-900, Brazil;2. Oral Pathology, Department of Stomatology, Public Oral Health, and Forensic Dentistry, Ribeirão Preto Dental School (FORP/USP), University of São Paulo – Avenida do Café, S/N, Ribeirão Preto, São Paulo, 14040-904, Brazil;3. Department of Pediatric Dentistry, School of Dentistry, University of El Salvador, San Salvador, El Salvador;1. Department of Pediatric Dentistry, Kanagawa Dental University, Yokosuka, Japan;2. Kanagawa Dental University, Yokosuka, Japan;3. Department of Restrative Dentistry, Kanagawa Dental University, Yokosuka, Japan;4. Department of Pathology and Histomorphology, Kanagawa Dental University, Yokosuka, Japan;5. Division of International Dentistry, Department of Comprehensive Dentistry, Kanagawa Dental University, Yokosuka, Japan;1. Department of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi Minami-ku Hiroshima-city, Hiroshima, 734-8553, Japan;2. Medical Corporation Tanpopo Pediatric Dental Clinic, 3-21-26 Gion Asaminami-ku Hiroshima-city, Hiroshima, 731-0138, Japan;3. Medical Corporation Shoseikai Nobeoka Kids and Parent Dental Clinic, 1-1-11 Midorigaoka Nobeoka-city Miyazaki, 882-0863, Japan;1. Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, Yokohama, Japan;2. Department of Oral Anatomy, Tsurumi University School of Dental Medicine, Yokohama, Japan |
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| Abstract: | IntroductionComparing oral health of cancer to non-cancer children proves that cancer and its treatment can cause oral complications.DesignTwo groups of children, 50 treated for cancer, and 51 cancer-free, at two different centers, signed informed consent forms. Both the examination of teeth, oral functions and soft tissue with a questionnaire including the patients’ demographic characteristics, medical history, dietary and oral hygiene, and changes due to the oncologic treatment allowed gathering data.ResultsThe two groups had no demographic nor socio-economic differences. Dietary habits were not significantly different. Daily brushing was more frequent in cancer-free (96.1%) versus sick (76%) children. Oral hygiene was poor (34%) or very poor (24%) in cancer patients and average for non-cancer subjects (68.6%). Cancer patients had more caries, without significant differences between groups. Gingiva was healthy in 96.1% of non-cancer and 76% of cancer patients (p = 0.044). In cancer patients, intra-oral soft tissue lesions were aphtous ulcers (52.9%), candidiasis (23.5%), and herpes (17.6%). Xerostomia was significantly different (p = 0.001) between cancer (32%) and non-cancer subjects (3.9%). Chemotherapy alone is an independent predictor of poor oral health (HR 17.7, 95% CI [5.2–60.9], p < 0.001).ConclusionCancer patients had poor oral health compared to non-cancer children, with insufficient knowledge concerning the relationship between oral and general health. Education programs, screenings and treatment at cancer centers may help reduce risks of complications. |
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| Keywords: | Cancer Cancer treatment Nutrition Oral health Pediatric |
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