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Comparison of quality of life and psychological distress in patients with tongue cancer undergoing a total/subtotal glossectomy or extended hemiglossectomy and free flap transfer: a prospective evaluation
Institution:1. Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan;2. Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan;3. Institute for Glyco-core Research (iGCORE), Nagoya University, Nagoya, Japan;4. Department of Otorhinolaryngology, Head and Neck Surgery, Aichi Medical University, Aichi, Japan;1. Department of Oral and Maxillofacial Surgery, University of São Paulo School of Dentistry, São Paulo-SP, Brazil;2. Private Practice in Oral and Maxillofacial Surgery, São Paulo-SP, Brazil;1. Department of Oral and Maxillofacial Radiology, Peking University School and Hospital of Stomatology, Beijing, PR China;2. Department of Radiology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, Shandong, PR China;3. Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, PR China;1. School of Oral Surgery, Department of Medical Biotechnologies, University of Siena, Siena, Italy;2. Department of Maxillofacial Surgery, Faculty of Medicine and Surgery, University of Siena, Siena, Italy;1. Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, Guandong, China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, Guangdong, China.;2. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ibb University, Ibb, Yemen;3. Department of Oral and Maxillofacial Surgery, Lanzhou University Second Hospital, School of Stomatology, Lanzhou University, Lanzhou, China;1. Maxillofacial Institute, Teknon Medical Center, Barcelona, Spain;2. Department of Oral and Maxillofacial Surgery, Universitat Internacional de Catalunya (UIC), Barcelona, Spain;3. Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal;1. Department of Maxillofacial and Plastic Surgery, Intercommunal Hospital Centre of Villeneuve-St-Georges, Villeneuve-Saint-Georges, France;2. Department of Stomatology and Maxillofacial Surgery, University Hospital Treichville, Abidjan, Ivory Coast
Abstract:The aim of this study was to assess changes in the quality of life and psychological distress of patients with tongue cancer undergoing total/subtotal glossectomy (TG) or extended hemiglossectomy (HG) and free flap transfer. Differences between the two groups were compared using the Short Form 8-Item Health Survey (SF-8) and Hospital Anxiety and Depression Scale (HADS). Of the 43 patients with tongue cancer, 24 (56%) underwent TG and 19 (44%) underwent HG. The general health and social functioning scores in the SF-8 and depression in the HADS were significantly worse in the TG group than in the HG group at 12 months after surgery, indicating that patients in the TG group may experience social isolation and psychological distress, and have difficulty in employability even 12 months after surgery. In contrast, all items of the SF-8 in the HG group were nearly equal to those in the general population. Due to the extensive psychological impact on patients with tongue cancer who are planned for an extended resection, curative surgery with free flap transfer and multidisciplinary psychiatric support are essential to improve quality of life and manage psychological distress.
Keywords:Tongue neoplasms  Glossectomy  Free tissue flaps  Quality of life  Psychology
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