| AB-8型树脂对牛蒡苷吸附分离性能的研究 |
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| 引用本文： | 卢来春,张蓉,周世文,蒋学文.AB-8型树脂对牛蒡苷吸附分离性能的研究[J].第三军医大学学报,2007,29(5):439-441. |
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| 作者姓名： | 卢来春 张蓉 周世文 蒋学文 |
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| 作者单位： | 1. 第三军医大学新桥医院药学部,重庆,400037
2. 第三军医大学新桥医院临床药理基地,重庆,400037 |
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| 摘 要： | 目的 研究大孔吸附树脂分离纯化牛蒡子中牛蒡苷的性能.方法 采用HPLC法测定牛蒡苷的含量.考察大孔吸附树脂对牛蒡苷的吸附性能及洗脱参数.结果 AB-8型大孔吸附树脂对提取液中的牛蒡苷的最佳分离条件为:上柱液浓度为5.5 mg/ml;流速为2 BV/h,牛蒡苷的比吸附量为52.08 mg/g,50%乙醇洗脱率为93.8%;牛蒡苷纯度可达55.2%.结论 AB-8型大孔吸附树脂可用于牛蒡苷的分离富集.
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| 关 键 词： | 大孔吸附树脂 牛蒡子 牛蒡苷 吸附 分离 |
| 文章编号： | 1000-5404（2007）05-0439-03 |
| 修稿时间： | 2006-10-30 |
Adsorption and separation properties of AB-8 resin for purifying arctinin |
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| LU Lai-chun,ZHANG Rong,ZHOU Shi-wen,JIANG Xue-wen.Adsorption and separation properties of AB-8 resin for purifying arctinin[J].Acta Academiae Medicinae Militaris Tertiae,2007,29(5):439-441. |
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| Authors: | LU Lai-chun ZHANG Rong ZHOU Shi-wen JIANG Xue-wen |
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| Institution: | 1 Department of Pharmacy, 2 Base for Drug Clinical Trial, Xinqiao Hospital,Third Military Medical University,Chongqing 400037, China |
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| Abstract: | Objective To study the separation ability of AB-8 macroporous resin in the purification of arctinin in Fructus arctii. Methods HPLC was used to measure the content of arctinin, and the adsorption performance and the elution parameters were investigated. Results The optimal separation conditions were as follows: the concentration of Arctinin was 5.5 mg/ml with a flow rate of 2 BV/h, and 50% alcohol was used as eluant. The adsorption of Arctinin was 52.08 mg/g, and the elution ratio of arctinin was 93.8%, and the purity of arctinin reached 65.2%. Conclusion AB-8 resin can be used to refine the arctinin in the extraction of Fructus arctii. |
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| Keywords: | macroporous resin Fructus arctii arctinin adsorption separation |
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