k‐space water‐fat decomposition with T2* estimation and multifrequency fat spectrum modeling for ultrashort echo time imaging |
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| Authors: | Kang Wang MS Huanzhou Yu PhD Jean H Brittain PhD Scott B Reeder MD PhD Jiang Du PhD |
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| Institution: | 1. Department of Medical Physics, University of Wisconsin, Madison, Wisconsin, USA;2. Applied Science Laboratory, GE Healthcare, Menlo Park, California, USA;3. Applied Science Laboratory, GE Healthcare, Madison, Wisconsin, USA;4. Department of Radiology, University of Wisconsin, Madison, Wisconsin, USA;5. Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin, USA;6. Department of Medicine, University of Wisconsin, Madison, Wisconsin, USA;7. Department of Radiology, University of California, San Diego, California, USA |
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| Abstract: | Purpose: To demonstrate the feasibility of combining a chemical shift‐based water‐fat separation method (IDEAL) with a 2D ultrashort echo time (UTE) sequence for imaging and quantification of the short T2 tissues with robust fat suppression. Materials and Methods: A 2D multislice UTE data acquisition scheme was combined with IDEAL processing, including T2* estimation, chemical shift artifacts correction, and multifrequency modeling of the fat spectrum to image short T2 tissues such as the Achilles tendon and meniscus both in vitro and in vivo. The integration of an advanced field map estimation technique into this combined method, such as region growing (RG), is also investigated. Results: The combination of IDEAL with UTE imaging is feasible and excellent water‐fat separation can be achieved for the Achilles tendon and meniscus with simultaneous T2* estimation and chemical shift artifact correction. Multifrequency modeling of the fat spectrum yields more complete water‐fat separation with more accurate correction for chemical shift artifacts. The RG scheme helps to avoid water‐fat swapping. Conclusion: The combination of UTE data acquisition with IDEAL has potential applications in imaging and quantifying short T2 tissues, eliminating the necessity for fat suppression pulses that may directly suppress the short T2 signals. J. Magn. Reson. Imaging 2010;31:1027–1034. ©2010 Wiley‐Liss, Inc. |
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| Keywords: | ultrashort TE (UTE) ultrashort TE spectroscopic imaging (UTESI) IDEAL water‐fat separation T2* estimation artifact correction |
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