从复旦大学附属华山医院用药情况浅谈非甾体类抗炎药使用特点和趋势

目的:从复旦大学附属华山医院门诊用药情况分析各类非甾体类抗炎药(NSAIDs)的用药特点和趋势。方法:根据2000~2004年华山医院门诊药房所用的NSAIDs的品种、数量和金额,回顾性地分析比较DDDs、日均费用(DDDc)和金额。结果:5年中NSAIDs年处方总金额在80~120万元间波动上升,DDDc逐年上升。DDDs排位较前的为美洛昔康、双氯芬酸钠缓释制剂和布洛芬缓释制剂。2000年后品种数增加,新一代NSAIDs环氧化酶-2选择性抑制剂被引入临床使用。结论:NSAIDs长期使用都存在一定风险,传统NSAIDs的改良剂型以及安全性更可靠的NSAIDs是研究方向。

The features and trends of using NSAIDs with the statistics in Huashan Hospital affiliated to Fudan University

Objective: To analyze the situation and trend of using NSAIDs.Methods: According to the varieties,amount,purchase cost of NSAIDs in outpatient department of Huashan Hospital affiliated to Fudan University,DDDs,DDDc and purchase cost were analyzed retrospectively.Results: The total purchase costs were 800-1 200 thousand Yuan every year during 2000-2004,and DDDc has been increasing year by year.Meloxicam,diclofenac and ibuprofen sustained-release preparation ranked top 3 on the DDDs list.A new kind of NSAIDs,named selective cyclooxygenase-2 inhibitors has been introduced to the clinical use since 2000.Conclusion: There are always some hazards to use NSAIDs for a long time.So the aim of research is to improve the formulation of NSAID products and get the new and safe NSAIDs.