SWI对急性脑梗死静脉溶栓治疗决策的价值

目的 探讨磁共振磁敏感加权成像(SWI)序列在急性脑梗死静脉溶栓治疗决策中的价值.方法 依据SWI扫描是否存在脑组织微量出血(CMBs),将35例急性脑梗死患者分为实验组(存在CMBs)14例和对照组(无CMBs)21例.静脉溶栓后,通过SWI检测计数发生出血性转化(HT)的例数,比较实验组和对照组之间发生HT是否存在统计学差异(P<0.05).结果 静脉溶栓治疗后,实验组14例梗死灶中12例发生HT,对照组21例仅2例发生HT,2组间HT发生存在统计学差异(P<0.05).结论 磁共振SWI能敏感检测CMBs的存在,间接评估血脑屏障(BBB)及血管壁状态,和时间窗一起作为静脉溶栓治疗方案的决策依据.

Value of SWI in intravenous thrombolytic therapy of acute cerebral infarction

Objective To investigate the decisional value of susceptibility weighted imaging(SWI) in intravenous thrombolytic therapy to acute cerebral infarction.Methods According to cerebral microbleeds(CMBs) by SWI, 35 cases of acute cerebral infarction in window-time random were divided into experimental group(14 cases) with CMBs and control group(21 cases) without CMBs.After intravenous thrombolysis, the number of hemorrhagic transformation(HT) was counted by SWI, and statistic difference was compared between the experimental group and the control group(P<0.05).Results After intravenous thrombolytic therapy of acute infarction,12 cases with HT among experimental group, and only 2 cases with HT among control group, there was significant statistically difference between two groups(P<0.05).Conclusion SWI sequence has greater sensitivity in detecting CMBs,and can also assess the state of blood brain barrier(BBB) and vascular wall indirectly.It plays a very important role in giving a decision in the treatment of intravenous thrombolytic with window-time.