双能CT Volume软件定量分析尿酸盐结晶的临床应用

目的 利用双能CT(DECT)中Volume软件对双能量成像尿酸盐结晶的体积进行定量分析,评价其临床应用价值.方法 回顾性分析60例符合美国风湿病协会(ACR)诊断标准的痛风患者的DECT扫描结果,由2位高年资放射科医师利用Volume软件分别对尿酸盐结晶的体积进行定量分析,并对结果进行统计学分析.结果 60例患者共扫描了72对关节,其中43对足踝关节,出现尿酸盐结晶40对,平均体积(0.621±0.742)cm3;19对膝关节,出现尿酸盐结晶18对,平均体积(0.842±1.086)cm3;10对手腕关节,出现尿酸盐结晶10对,平均体积(0.796±0.583)cm3.2位医师对尿酸盐结晶体积的统计无统计学差异(P>0.05).有4例患者规律服药后复查CT显示尿酸盐结晶体积均有减少.结论 DECT的Volume软件可对尿酸盐结晶进行定量分析,可重复性较强,对临床诊断痛风及疗效监测具有较高的应用价值.

Clinical value of dual-energy CT Volume software in quantitative analysis of urate crystals

Objective To assess the clinical value of dual-energy CT (DECT) Volume software in quantitative analysis of urate crystals.Methods The DECT data of 60 gout patients based on the American College of Rheumatology diagnostic criteria were analyzed retrospectively.The volumes of urate crystals were quantitatively analyzed by using Volume software with two senior radiologists.The results were statistically analyzed.Results Seventy-two joints of 60 gout patients were scanned by DECT.40 of 43 joints had urate crystals in foot and ankle with the average volume of (0.621±0.742) cm3;18 of 19 joints had urate crystals in knee with the average volume of (0.842±1.086) cm3;10 of 10 joints had urate crystals in hand and wrist with the average volume of (0.796±0.583) cm3.There was no statistical difference for volume measurement between two doctors (P>0.05).The volumes of urate crystals in 4 patients with regular medication were reduced.Conclusion Volume software of DECT can quantitatively analyze urate crystals with a good repeatability, which has high application value in clinical diagnosis and treatment monitoring of gout.