CTA对脑卒中家族史人群颅内动脉瘤的筛查研究

目的 探讨CT血管造影(CTA)对脑卒中家族史人群颅内动脉瘤的筛查状况.方法 招募200例本院就诊的有阳性脑卒中家族史的志愿者.其中男108例,女92例,统一接受头颅CTA检查、体格检查及实验室检查,并对检查结果进行分析研究.结果 200例志愿者在人口学特征,既往病史和体质检测方面,男、女志愿者之间差异无统计学意义(P＞0.05);在生活方式上,男性志愿者的吸烟率和饮酒率均高于女性志愿者(P＜0.05),女性志愿者的用药率高于男性志愿者(P＜0.05).200例有脑卒中家族史的志愿者中,27例(13.5％)患有颅内动脉瘤,其中男13例(12.03％)、女14例(15.22％),有1例发生动脉瘤破裂蛛网膜下腔出血,剩余26例均未发生动脉瘤破裂,未破裂动脉瘤患病率为13％.患有颅内动脉瘤的27例中共29个动脉瘤,有2例患有2个动脉瘤,为多发动脉瘤.动脉瘤直径＜3 mm 7个(24.14％),3～7 mm 12个(41.38％),＞7 mm 10个(34.48％).动脉瘤形态分类为梭形7个(24.14％),囊性22个(75.86％),小血滴样3个(10.34％).结论 头颅CTA是检查颅内动脉瘤无创有效的方法,所提供的诊断信息特别适用于急症患者的动脉瘤筛查.

The study of intracranial aneurysms screened by CTA among the population with family history of stroke

Objective To explore the status of intracranial aneurysms screened by CTA among the population with family history of stroke.Methods 200 patients including 108 men and 92 women in our hospital were involved,who had a family history of stroke.Head CTA examination,physical examination and laboratory tests were performed.Results 200 male and female had no statistical significance in demographic characteristics,past medical history and physical testing (P＞0.05);in lifestyle,smoking and drinking prevalence among male were higher than female (P＜0.05),and drug-usage rate of female were higher than male (P＜0.05).27 cases (13.5 ￥)had intracranial aneurysms,including 13 male cases (12.03 ％) and 14 females cases(15.22 ％),and there was one occurred aneurysm rupture and subarachnoid hemorrhage,the prevalence rate of aneurysm rupture was 87％.The 27 intracranial aneurysms cases had 29 CPC aneurysms,with 2 cases had two aneurysms.The number of aneurysm diameter ＜3 mm were 7 (24.14％),3 7 mm diameter were 12 (41.38％),and ＞7 mm were 10 (34.48％).Classified by the morphology,there were 7 (24.14％) fusiform aneurysm,22 (75.86％) cystic,3 (10.34％) small drops of blood sample.Conclusion CTA is a noninvasive and effective method for intracranial aneurysm,can provide additional valuable diagnostic information particularly for emergency of aneurysm screening.