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Ribosomal RNA evidence of ocular Chlamydia trachomatis infection following 3 annual mass azithromycin distributions in communities with highly prevalent trachoma |
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| Authors: | Keenan Jeremy D Ayele Berhan Gebre Teshome Moncada Jeanne Stoller Nicole E Zhou Zhaoxia Porco Travis C McCulloch Charles E Gaynor Bruce D Emerson Paul M Schachter Julius Lietman Thomas M |
| Affiliation: | FI Proctor Foundation, Department of Ophthalmology, University of California, San Francisco, CA 94143-0412, USA. jeremy.keenan@ucsf.edu |
| Abstract: | Twelve trachoma-hyperendemic communities were treated with 3 annual mass azithromycin distributions. Children aged 0-9 years were monitored 1 year following the third treatment. An RNA-based test detected ocular chlamydial infection in more children than did a DNA-based test (6.9% vs 4.2%), and in a larger number of communities (8 vs 7). |
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