| 石榴皮抗氧化物质提取及其体外抗氧化作用研究 |
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| 引用本文： | 李云峰,郭长江,杨继军,韦京豫,徐静,程霜. 石榴皮抗氧化物质提取及其体外抗氧化作用研究[J]. 营养学报, 2004, 26(2): 144-147 |
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| 作者姓名： | 李云峰 郭长江 杨继军 韦京豫 徐静 程霜 |
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| 作者单位： | 卫生学环境医学研究所,天津,300050 |
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| 摘 要： | 目的: 研究石榴皮提取物体外清除自由基的作用及对低密度脂蛋白(LDL)氧化的影响。方法: 采用 -2O、·OH、ROO·等自由基的生成体系,研究石榴皮提取物清除自由基的活性,并进一步采用LDL体外氧化模型,研究对LDL氧化的抑制作用,并与石榴果汁提取物相比较。结果: 两种提取物均可以有效清除 -2O、稯H、ROO纷杂苫种芁DL氧化,其活性具有剂量效应关系;果皮提取物的各种活性均强于果汁提取物。结论: 石榴皮所含天然抗氧化物质能有效清除 -2O、稯H、ROO返茸杂苫种芁DL氧化,因而可能具有抑制动脉粥样硬化(AS)的作用。
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| 关 键 词： | 石榴皮 抗氧化 自由基 低密度脂蛋白 |
| 文章编号： | 0512-7955(2004)02-0144-04 |
| 修稿时间： | 2003-05-16 |
STUDY ON EXTRACTION OF ANTIOXIDANTS IN POMEGRANATE PEEL AND ITS ANTIOXIDANT ACTIVITIES IN VITRO |
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| LI Yun-feng,GUO Chang-jiang,YANG Ji-jun,WEI Jing-yu,XU Jing,CHENG Shuang. STUDY ON EXTRACTION OF ANTIOXIDANTS IN POMEGRANATE PEEL AND ITS ANTIOXIDANT ACTIVITIES IN VITRO[J]. Acta Nutrimenta Sinica, 2004, 26(2): 144-147 |
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| Authors: | LI Yun-feng GUO Chang-jiang YANG Ji-jun WEI Jing-yu XU Jing CHENG Shuang |
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| Abstract: | Objective: To investigate the free radical scavenging activities of the extract from pomegranate peel and compare with that from juice. Methods: Free radicals (-2O, 稯H and ROO? scavenging activities were investigated in different special chemical systems. Its inhibition activity on LDL oxidation was studied with LDL oxidation model in vitro. Results:Both extracts had strong abilities to scavenge -2O, 稯H and ROO?radicals and prevent LDL oxidation in dose-dependent manner. The extract from peel showed higher activities than that from juice. Conclusion: The natural antioxidants in the extracts of pomegranate peel or juice can effectively scavenge -2O, 稯H and ROO?radicals, and prevent LDL oxidation significantly, especially much more in the former. |
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| Keywords: | pomegranate peel antioxidant free radical low-density lipoprotein |
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