Pancreatic tuberculosis: a rare cause of pseudoneoplastic obstructive jaundice |
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Authors: | Beaulieu Sandrine Chouillard Elie Petit-Jean Bruno Vitte René-Louis Eugene Claude |
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Institution: | Service d'Hépato-Gastroentérologie, Centre hospitalier intercommunal de Poissy/Saint Germain-en-Laye, Poissy. sbeaulieu@chi-poissy-st-germain.fr |
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Abstract: | Isolated pancreatic tuberculosis is rare, and can mimic pancreatic carcinoma. We report a case of pseudoneoplastic pancreatic tuberculosis revealed by an obstructive jaundice in a 35-Year-old man. Surgical pancreatic histopathology showed a caseating granulomatous inflammation and diagnosis was confirmed by detection of Mycobacterium tuberculosis DNA using specific polymerase chain reaction-based assay (PCR). The patient was successfully treated with quadruple antituberculous therapy. In the context of the diagnostic work-up of a hypodense pancreatic mass, the diagnosis of tuberculosis relies on the presence of pancreatic caseating granulomas, that can be obtained by endosonography-guided biopsy, thus avoiding laparotomy. |
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