Allergic contact dermatitis to tulips: An example of enantiospecificity |
| |
Authors: | C. Papageorgiou J.-L. Stampf C. Benezra |
| |
Affiliation: | (1) Laboratoire de Dermatochimie, Associé au CNRS, Université Louis Pasteur, Clinique Dermatologique, CHU, F-67091 Strasbourg, France |
| |
Abstract: | Summary Allergic contact dermatitis (ACD), an immunological reaction of the skin resulting from contact with reactive compounds occurring in plants was shown to the enantiospecific (animals sensitized to a compound do not react to its nonsuperimposable mirror image). Thus, when guinea pigs were experimentally sensitized to (+)-tulipalin B (a compound present in tulip bulbs) they did not react to its enantiomer, (-)-tulipalin B. This was also true for (+)- and (-)--hydroxy--methyl--methylene--butyrolactones. |
| |
Keywords: | Allergic contact dermatitis Enantiospecifity |
本文献已被 SpringerLink 等数据库收录! |
|