缺氧对犬肺循环血流动力学和流变学参数的影响

本文观察了缺氧引起的犬肺循环血流动力学及流变学参数的变化。结果表明：缺氧能显著降低心输出血流量，造成肺动脉高压，经计算获得肺血管阻力明显增加。缺氧还使犬的全血粘度增加，从高、低切变率条件下还原粘度的明显改变上看，这种全血粘度的增加与红细胞刚性指数和聚集指数的上升直接相关。

Effects of hypoxia on hemodynamics and hemorrheology of pulmonary circulation in the dog

The change of hemodynamics and hemorrheology induced by hypoxia challenge in the dog were investigated. The results showed that hypoxia caused significant decrease of cardiac output, increased pulmonary artery pressure and pulmonary vascular resistance. Hypoxia also caused increase of blood viscosity. In terms of changes of the reduced viscosity is directly related to the deformation and agglutination properties of red blood cells.