舒血宁注射液联合氢氯吡格雷治疗急性脑梗死的疗效研究

目的:分析对急性脑梗死患者实施舒血宁注射液联合氢氯吡格雷治疗的效果。方法:择取80例择取急性脑梗死患者,将其随机分为对照组和研究组各40例,对照组实施氢氯吡格雷治疗,研究组实施舒血宁注射液联合氢氯吡格雷治疗,对照分析两组临床效果。结果:从血液流变学指标来看,治疗后研究组全血低切黏度、全血高切黏度、血小板聚集率、血浆黏度均优于对照组(P<0.05);从神经功能指标来看,治疗后研究组MBP、H-FABP、NSE、GFAP均优于对照组(P<0.05);从相关细胞因子水平变化来看,治疗后研究组sVCM-1、TNF-α、IL-18均优于对照组(P<0.05)。结论:对急性脑梗死患者实施舒血宁注射液联合氢氯吡格雷治疗的效果确切。

Effect of Shuxuening Injection Combined with Hydroclopidogrel on Acute Cerebral Infarction

Objective:To analyze the effect of Shuxuening injection combined with hydroclopidogrel in the treatment of acute cerebral infarction.Methods:80 patients with acute cerebral infarction were selected and randomly divided into two groups.The control group(40 cases)was treated with hydroclopidogrel and the study group(40 cases)was treated with Shuxuening injection combined with hydroclopidogrel,then the clinical effects of two groups were compared.Results:In terms of hemorheology indexes,the whole blood low shear viscosity,whole blood high shear viscosity,platelet aggregation rate and plasma viscosity in the study group were all better than those in the control group(P<0.05).In terms of neurological indexes,MBP,H-FABP,NSE and GFAP in the study group were all better than those in the control group after treatment(P<0.05).In terms of changes of related cytokines,svcm-1,TNF-αand IL-18 in the study group after treatment were better than those in the control group(P<0.05).Conclusion:Shuxuening injection combined with hydrochloclopidogrel is effective in the treatment of acute cerebral infarction.