| 五味清热饮预防发热药效学研究 |
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| 引用本文： | 蔡长春,李景苏.五味清热饮预防发热药效学研究[J].华北国防医药,2006,18(6):395-396. |
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| 作者姓名： | 蔡长春 李景苏 |
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| 作者单位： | 解放军白求恩国际和平医院药剂科,石家庄050082 |
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| 摘 要： | 目的:研究五味清热饮在大鼠的预防发热作用.方法:大鼠口服正柴胡饮及高、中、低剂量五味清热饮30分钟后,皮下注射2,4-二硝基苯酚30 mg/kg致大鼠发热,观察0.5、1.0、1.5、2.0、2.5、3.0、4.0及5.0 h大鼠体温变化.结果:与对照组比较,五味清热饮高、中、低剂量组于给药后0.5、1.0、1.5、2.0、2.5及3.0 h对大鼠体温均具有非常显著的降低作用(P＜0.01).结论:五味清热饮对2,4-二硝基苯酚致大鼠发热有明显的预防作用.
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| 关 键 词： | 植物制剂 发热 预防 中药药效学 大鼠 Wistar |
| 文章编号： | 1009-0878（2006）06-0395-02 |
| 修稿时间： | 2006年8月16日 |
Study on Pharmacodynamics in Preventing Fever by Taking Wuweiqingreyin |
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| CAI Chang-Chun,LI Jing-Su.Study on Pharmacodynamics in Preventing Fever by Taking Wuweiqingreyin[J].Medical Journal of Beijing Military Region,2006,18(6):395-396. |
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| Authors: | CAI Chang-Chun LI Jing-Su |
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| Institution: | Pharmaceutical Department, Bethune International Peace Hospital of PLA , Shijiazhuang,050082, China |
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| Abstract: | Objective:: To study the effect of Wuweqingreyin on preventing fever in rats.Methods:Thirty minutes after the oral administration of high,medium or low doses of Wuweiqingreyin respectively,2,4-dinitrophenol(30 mg/kg)was injected to induce fever in rats.Then body temperature was recorded 0.5,1.0,1.5,2.0,2.5,3.0,4.0 and 5.0 h after the injection.Results:Compared with that of the saline control group,there was an obvious drop in the body temperature in Wuweiqinreyin groups.Conclusion:Wuweiqingreyin has an obvious effect in preventing the rat fever induced by 2,4-dinitrophenol. |
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| Keywords: | Plant preparations Fever Prevention Chinese herbal pharmaeodynamics Rats Wistar |
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