祛瘀化痰汤治疗2型糖尿病合并血脂代谢异常85例疗效观察

目的 探讨祛瘀化痰汤治疗2型糖尿病合并血脂代谢异常的临床疗效.方法 将85例患者随机分为治疗组45例和对照组40例.对照组采用皮下注射胰岛素,治疗组在对照组治疗基础上口服祛瘀化痰煎剂,两组均4周为1个疗程,连续治疗2个疗程,观察两组患者治疗前后TC、TG、LDL-C、HDT-C变化.结果 治疗组治疗后血脂变化明显优于对照组(t=0.01l,P<0.05).结论 祛瘀化痰汤治疗2型糖尿病合并血脂代谢异常有效.

Clinical study on the Treatment of 85 cases of Type 2 Diabetes Mellitus Combined with Abnormal Metabolism of Lipid with Quyuhuatan Decoction

Objective To explone the therapeutic effect and mechanism of Quyuhuatan decoction in treating type 2 diabetes mellitus combined with abnormal metabolism of lipid. Methods 85 cases of type 2 diabetes mellitus combined with abnormal metabolism of lipid were recruited into a control group and a treatment group randomly. The treatment group (45cases) was treated with Quyuhuatan decoction and subcutaneous insulin injection while the control group(40cases) was treated with subcutaneous insulin injection exclusively. Both groups received the treatment for for 8 weeks. The result of TC, TG, LDL-C, and HDT-C were observed before and after the treatment. Results The improvement of blood lipid in the treatment group was superior to that in the control group (t=0.011, P<0.05) . Conclusion Quyuhuatan decoction is effective in treating type 2 diabetes mellitus combined with abnormal metabolism of lipid. The mechanism might be related with its cutting off pathological paths of hyperlipidemia.