未成年人胰腺实性假乳头状瘤临床特点及预后

 摘要：目的 探讨未成年人胰腺实性假乳头状瘤疾病特点、治疗方法及预后。方法 结合文献及我院收治的四例未成年人胰腺实性假乳头状瘤病例，分析未成年人胰腺实性假乳头状瘤的临床表现、病理特点、与性激素受体及生长发育的关系、治疗方法及预后。结果 未成年人胰腺实性假乳头状瘤的临床表现与成人大致相同，但表现出明显的生长发育障碍，如本组病例中各患者的第二性征发育迟滞等表现。手术切除肿瘤后生长发育迟缓可得到逆转。治疗方法为保证肿瘤完整切除的前提下保留尽可能多的脏器，以减少对术后生长发育的影响。本组四例患者手术治疗的前提均为手术创伤最小化。未成年人胰腺实性假乳头状瘤预后目前尚无定论。结论 在对未成年人胰腺实性假乳头状瘤的诊治过程中应充分考虑到患者的未成年特点，以保证患者术后继续生长发育及长期生活质量。

Clinical Characteristics and Prognosis of Minor Solid Pseudopapillary Tumor of the Pancreas

ABSTRACT: Objective: To investigate the characteristics, treatment and prognosis of solid pseudopapillary tumor of the pancreas in the minor. Method: Combining minor solid pseudopapillary tumor of the pancreas cases in literatures and 4 cases of our hospital, we analyzed the clinical and pathological features, and the relationship with sex hormone receptors, the growth and development, treatment and prognosis. Results: the clinical manifestations of solid pseudopapillary tumor of the pancreas in minor were same as adults, but the minors showed significant growth retardation which can be reversed after the tumor surgical removal, like 4 patients all showed secondary sex characteristics of retardation in the group. The protocol of surgical treatment was to ensure complete removal of the tumor and keep the healthy organs as much as possible which reduced the impact to the postoperative growth and development.The premise of operation therapy in the 4 cases is minimization of operation trauma. Minor solid pseudopapillary tumor of the pancreas prognosis has not been determined. Conclusion: the diagnosis and treatment of minor solid pseudopapillary tumor of the pancreas should be fully taken into account the characteristics of the minor to ensure that patients can continue long-term growth and development and the quality of life.