The ocular hypotensive effect of late pregnancy is higher in multigravidae than in primigravidae |
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| Authors: | I A Qureshi X R Xi T Yaqob |
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| Institution: | (1) Department of Biochemistry, Rawalpindi Medical College, Rawalpindi, Pakistan, PK;(2) c/o Mukhtar Ahmad, 20-A New Lalazar-1, Phase-11, Lane No. 5, Morga Post Office Near Fauji Foundation College, Behind UN Office, Rawalpindi, Pakistan, PK;(3) Department of Biochemistry, Shaghai Medical University, Shanghai, PR China, CN |
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| Abstract: | · Background: Systemic hypertension and degenerative vascular disease are more common in multigravidae than in primigravidae.
The present study investigated whether the known ocular hypotensive effect of late pregnancy is influenced by the number of
pregnancies. · Methods: Intraocular pressure (IOP) was measured in normotensive third-trimester primigravidae and multigravidae
along with nulligravida controls by means of the Goldmann applanation tonometer. Depending upon the number of previous pregnancies,
multigravidae were divided into four subgroups. · Results: The IOP of the pregnant group (primigravidae and multigravidae
together) was (mean±SEM) 2.1±0.07 mmHg (P<0.001) lower than in the nulligravida control group. The IOP of nulligravidae was 1.7±0.06 mmHg (P<0.001) and 2.5±0.01 mmHg (P<0.001) higher than in third-trimester primigravidae and multigravidae, respectively. In all subgroups of multigravidae IOP
was significantly lower (P<0.02) than in primigravidae. The differences among different subgroups of multigravidae were statistically insignificant. · Conclusions:
Gravidity influences IOP and should be taken into account in future research.
Received: 14 August 1997 Revised version received: 4 May 1998 Accepted: 26 May 1998 |
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