流浪与正常住院精神障碍患者常见抗原抗体检测结果对照研究

目的:了解流浪乞讨精神障碍患者常见抗原抗体阳性携带情况。方法:对2005年10月至2009年9月在南京市青龙山精神病院住院的流浪精神障碍患者701例采用金标记免疫分析技术(胶体金法)检测乙肝五项、抗HIV、抗Tp抗体;采用ELISA法检测抗HAV、抗HCV抗体,同期正常住院的460例精神病患者为对照组,并对检测结果进行统计学分析。结果:701例流浪精神障碍患者抗Tp抗体阳性率4.1%(其中男性2.2%,女性6.2%,女性显著高于男性,P<0.01),HBV总感染率45.4%,抗-HBs阳性率31.8%,显著高于对照组(P<0.01);HBsAg阳性率9.3%,抗-HBc阳性率19.0%,高于对照组(P<0.05);抗-HCV阳性率2.4%,HBeAg阳性率1.9%,抗-HBe阳性率5.8%,两组间差异无显著性(P>0.05);流浪精神障碍患者发现1例抗-HAV阳性和1例抗-HIV阳性。结论:流浪乞讨精神障碍患者是某些传染病感染的高危人群,女性流浪精神障碍患者是梅毒感染的高危人群,应该常规血清标志物检查,加强监管,积极预防和治疗。

Comparative study of common antigen-antibody test results in Wandering mental disorders and psychotic inpatients

Objective:To explore the vagrants and beggars patients with mental disorders carry common antigen-antibody-positive cases.Methods:To detected five of each patients hepatitis B,anti-HIV,anti-Tp antibody used by gold immunochromatographic assay(Colloidal Gold) in 701 cases of Wandering mental disorders in Qinglongshan mental hospital in Nanjing from October 2005 to September 2009,by ELISA detection of anti HAV,anti-HCV antibodies,and 460 psychotic inpatients at the same period as control group were involved i...