| 原发性肝癌的CT灌注成像 |
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| 引用本文： | 周作福,黄洪磊,徐彪,林碧金,刘振华,杨家友,邱友才.原发性肝癌的CT灌注成像[J].中国医学影像技术,2006,22(2):272-274. |
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| 作者姓名： | 周作福 黄洪磊 徐彪 林碧金 刘振华 杨家友 邱友才 |
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| 作者单位： | 福建省南平市第一医院放射科,福建南平,353000 |
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| 基金项目： | 福建省教育厅科研项目(JB04150)。 |
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| 摘 要： | 目的研究原发性肝癌CT灌注参数的改变和临床价值。方法本组78例行肝血流的CT灌注扫描,其中原发性肝癌组70例、正常组8例。应用去卷积算法模式计算相应病变区域的血流量(BF)、血容量(BV)、平均通过时间(MTT)、毛细血管通透性(PS)、肝动脉指数(HAF),来评价肝癌的血流动力学状态。结果70例原发性肝癌患者HAF、BF明显高于正常组织,而MTT明显降低;BV和PS值与正常组织无显著差异。结论肝癌CT灌注参数(HAF、BF和MTT)可有效的评价原发性肝癌的血流状态,具有重要的临床应用价值。
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| 关 键 词： | 体层摄影术 X线计算机 灌注成像 参数 癌 肝细胞 |
| 文章编号： | 1003-3289（2006）02-0272-03 |
| 收稿时间： | 2005-05-29 |
| 修稿时间： | 2005-11-04 |
CT perfusion imaging of hepatocellular carcinoma |
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| ZHOU Zuo-fu,HUANG Hong-lei,XU Biao,LIN Bi-jin,LIU Zhen-hu,YANG Jia-you and QIU You-cai.CT perfusion imaging of hepatocellular carcinoma[J].Chinese Journal of Medical Imaging Technology,2006,22(2):272-274. |
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| Authors: | ZHOU Zuo-fu HUANG Hong-lei XU Biao LIN Bi-jin LIU Zhen-hu YANG Jia-you and QIU You-cai |
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| Institution: | Department of Radiology, Nanping First Hospital of Fujian, Nanping 353000, China |
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| Abstract: | Objective To study the changes of perfusion parameters in multislice CT perfusion imaging of hepatocellular carcinoma (HCC). Methods Dynamic CT scan with singe-location sequence was performed in 78 individuals including 70 patients with HCC and 8 control subjects. The liver perfusion parameters, such as blood flow (BF), blood volume (BV), mean transit time (MTT), permeability surface (PS) and hepatic arterial fraction (HAF), were calculated. Results Compared HCC with controls, HAF and BF in HCC group increased significantly, and MTT decreased significantly. BV and PS did not differ between the two groups. Conclusion The changes of hepatic perfusion parameters (HAF, BF and MTT) were of great value in evaluating the hemodynamics of HCC. |
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| Keywords: | Tomography X-ray computed Perfusion imaging Parameters Carcinoma hepatocellular |
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