| 肺炎支原体在咳嗽变异型哮喘发病中的作用 |
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| 引用本文： | 李迎利,赵红红,尚宁.肺炎支原体在咳嗽变异型哮喘发病中的作用[J].临床肺科杂志,2003,8(2):101-102. |
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| 作者姓名： | 李迎利 赵红红 尚宁 |
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| 作者单位： | 210002,解放军空军南京医院呼吸科 |
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| 摘 要： | 目的 探讨咳嗽变异型哮喘(Cough Variant asthma,CVA)发病机制中肺炎支原体(MP)的作用。方法 观察CVA发作期及缓解期痰MP培养及嗜酸粒细胞(EOS)测定，同时测定FEVl及PEF的变化。结果 48例CVA患发作期中28例(58％)存在MP感染，其痰中EOS水平发作期较缓解期显升高(P＜0．05)。45例发作期FEVl及PEF＜80％正常值，42例支气管扩张试验FEVl和PEF值增加＞25％。结论 48例CVA中58％存在MP感染，证实了MP是CVA发病的重要病原体。
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| 关 键 词： | 肺炎支原体 咳嗽变异型哮喘 发病机制 治疗 阿奇霉素 皮质激素 |
| 修稿时间： | 2002年9月1日 |
The Role of Mycoplasma Pneumoniae in Cough Variant Asthma. |
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| Li Yingli,Zhao Honghong,Shang Ning.The Role of Mycoplasma Pneumoniae in Cough Variant Asthma.[J].Journal of Clinical Pulmonary Medicine,2003,8(2):101-102. |
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| Authors: | Li Yingli Zhao Honghong Shang Ning |
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| Institution: | Li Yingli Zhao Honghong Shang Ning Department of Respiratory Disease,Nanjing Airforce Hospital of PLA,Nangjing 210002 |
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| Abstract: | Objective To investigate the role of mycoplasma pneumoniae(Mp)in cough variant asthma (CVA).Methods The Mp cultured and eosinophili(Eos) levels of the sputum and pulmonary fuction test(pesk flow) were performed to identify the CVA.Results The Mp were cultured in 28 subjects (58%) with an acute CVA.The Eos levels of the sputum were significantiy higher than the redtore conrelescence:P<0.05.Pulmonary function test The FEV1.0% and PEF% were greatly reduced to (80%) in the 41 cases with CVA.Followed by grouchial dilation test FEV1.0% PEF%.Were increased 25 perceut.Conclusions The mycoplasma Pneumoniae in cough variant asthma was important causative agent,by essinophil might and airway uppuer skin damagieg Partrcpate in development of air way imflammation and airway by Perresponsiveness. |
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| Keywords: | Cough Asthma mycoplasma pneumoniae |
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