2005年山东省部分健康人群脑膜炎奈瑟氏菌带菌状况调查 |
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引用本文: | 李漫时,王敏,颜丙玉,宋立志,肖作奎,张丽,许青,李震.2005年山东省部分健康人群脑膜炎奈瑟氏菌带菌状况调查[J].预防医学文献信息,2009(1):47-48. |
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作者姓名: | 李漫时 王敏 颜丙玉 宋立志 肖作奎 张丽 许青 李震 |
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作者单位: | 山东省疾病预防控制中心,山东济南250014 |
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摘 要: | 目的]了解山东省健康人群流行性脑膜炎(流脑)流行期脑膜炎奈瑟氏菌(Nm)带菌情况及菌株药物敏感性,为制定防治措施提供参考。方法]2005年2~4月,在山东省分层整群抽取5个县(市、区)不同年龄健康人群进行咽部带菌调查,对分离的Nm菌株进行药物敏感性测定。结果]检测1 434人,检出Nm带菌者33人,带菌率为2.30%。带菌率,0岁、1~2岁、3~4岁、5~9岁、10~14岁、15~24岁、25~34岁、35~44岁和45岁以上各组分别为0.60%~5.46%(P〈0.05) 男性为3.53%,女性为1.10%(P〈0.01) 郯城县、高密市、济南市历下区、嘉祥县和临邑县为0.73%~3.73%(P〉0.05)。分离的33株Nm菌株中,A群13株,B群7株,C群6株,I群3株,W135群2株,Y群1株,X群1株。20株A、B、C群Nm菌株对环丙沙星、左氧氟沙星、复方新诺明均有不同程度的耐药。结论]山东省各个年龄组的健康人群均检出Nm带菌者,检出的菌株以A群为主,已发现耐药菌株。
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关 键 词: | 流行性脑脊髓膜炎 脑膜炎奈瑟氏菌 带菌率 药物敏感性 |
Survey of Neisseria Meningitidis Carrier Status among Healthy People in Shandong in 2005 |
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Institution: | LI Man-shi, WANG Min, YAN Bing-yu , et al. ( Shandong Center for Disease Control and Prevention, Ji'nan , 250014, Shandong , China) |
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Abstract: | Objective]To understand the distribution of Neisseria meningitidis( Nrn ) in healthy people in the epidemic phase in Shandong,to provide reference for disease control. Methods]The specimens of throat swabs were collected from healthy people in different age groups in 5 counties in the prevalent season by stratified sampling method. The Nm strains were isolated and identified,then antimicrobial susceptibility were tested. Results]33 Nrn strains were isolated from 1 434 specimens with the rate of 2.30%. It was different in every age group with the rate of 0.60%-5.46%(aged from 1 to 44 and over 45) ( P 〈0.05). The carrier rate was 3.53% in male and 1.10% in female ( P 〈0.01) ,and from 0.73% to 3.73 % ( P 〈0. 05)in Tancheng county,Gaomi city,Lixia district,Jiaxiang and Linyi counties. The proportion of Nrn , serogroup A,B,C,I,W135,X and Y was 13,7,6,3,2,1 and 1 respectively. 20 strains of serogroup A,B and C were resist- ance to ciprofloxacin,levofloxacin and compound sulfamethoxazole at different levels.Conclusion] Nrn strains were isola- ted from every age group, the dominant strain was still serogroup A, and the resistant strains have been detected. |
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Keywords: | Meningococcal meningitis Neisseria meningitidis Nrn Carrier Rate Antimicrobial susceptibility |
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